PHR1562

Trichloroethylene

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Trichloroethylene, TCE, Trichloroethene
• Linear Formula: ClCH=CCl₂
• CAS Number: 79-01-6
• Molecular Weight: 131.39
• Beilstein: 1736782
• EC Number: 201-167-4
• MDL number: MFCD00000838
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823471
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to USP 1601827
• vapor density: 4.5 (vs air)
• vapor pressure: 61 mmHg ( 20 °C)
• CofA: current certificate can be downloaded
• autoignition temp.: 770 °F
• packaging: ampule of 3x1.2 mL each
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• refractive index: n20/D 1.476 (lit.)
• bp: 86.7 °C (lit.)
• mp: −84.8 °C (lit.)
• density: 1.463 g/mL at 25 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: Cl\C=C(\Cl)Cl
• InChI: 1S/C2HCl3/c3-1-2(4)5/h1H
• InChI key: XSTXAVWGXDQKEL-UHFFFAOYSA-N

Description

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards. Trichloroethylene (TCE) is a chlorine containing organic compound, widely employed as an industrial solvent. It is formed as a major intermediate during the biodegradation of tetrachloroethylene (PCE) in a small anaerobic continuous-flow fixed film column.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA4478 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

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Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H315 - H317 - H319 - H336 - H341 - H350 - H412
• Precautionary Statements: P202 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Aquatic Chronic 3 - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1B - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point(F): does not flash
• Flash Point(C): does not flash