680303
Tetrahydrofuran solution
contains 20 % (v/v) 1,2-Propanediol
Synonym(s):
Butylene oxide, Oxolane, THF, Tetramethylene oxide
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About This Item
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form
liquid
Quality Level
contains
20 % (v/v) 1,2-Propanediol
impurities
≤0.20% water
0.02 meq/g Titr. acid
0.02 meq/g Titr. base
color
APHA: 1
density
0.914 g/mL at 25 °C
SMILES string
C1CCOC1
InChI
1S/C4H8O/c1-2-4-5-3-1/h1-4H2
InChI key
WYURNTSHIVDZCO-UHFFFAOYSA-N
Related Categories
General description
Tetrahydrofuran (THF) solution is THF in 20% (v/v) 1,2-propanediol. THF a saturated cyclic ester, is a water-miscible organic solvent. THF has been a widely used industrial solvent for varnishes and PVC (polyvinyl chloride), polymerization, electrochemistry, and pharmaceutical.
The product is a tetrahydrofuran (THF) solution containing 20%(v/v) 1,2-propanediol. THF, a saturated cyclic ester, is a water miscible organic solvent. The combustion studies of THF have been reported.
Application
- Self-Assembly of Polyoxometalate-Based Nanoparticle Surfactants in Solutions: Highlights the use of Tetrahydrofuran as a critical solvent in the synthesis and self-assembly of polyoxometalate-based nanoparticles, exploring applications that could impact multiple fields including polymer research, drug delivery systems, and nanostructured materials (Xia et al., 2024).
- Highly sensitive fluorescence turn-OFF and reversible chemical sensor for Hg(2+) ion based on pyrene appended 2-thiohydantoin: Tetrahydrofuran is used as a key solvent in the development of a novel fluorescence-based chemical sensor for mercury detection, demonstrating its application in environmental monitoring and safety in laboratory settings (Gawas et al., 2024).
- Effect of Plasma pretreatment and Graphene oxide ratios on the transport properties of PVA/PVP membranes for fuel cells: This research employs Tetrahydrofuran as a processing solvent in the creation of polyvinyl alcohol/polyvinylpyrrolidone membranes enhanced with graphene oxide, focusing on improvements in ion transport for fuel cell applications (Abdel-Hamed et al., 2024).
- Optimized Incorporation of Furan into Diketopyrrolopyrrole-Based Conjugated Polymers for Organic Field-Effect Transistors: Utilizes Tetrahydrofuran as a solvent to aid in the synthesis of novel conjugated polymers, potentially leading to advancements in organic electronics and polymer research (Neu et al., 2024).
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
Target Organs
Respiratory system
Supplementary Hazards
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
-6.2 °F - (THF)
Flash Point(C)
-21.2 °C - (THF)
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Highly selective hydrolytic kinetic resolution of terminal epoxides catalyzed by chiral (salen) CoIII complexes. Practical synthesis of enantioenriched terminal epoxides and 1,2-diols.
Schaus SE, et al.
Journal of the American Chemical Society, 124(7), 1307-1315 (2002)
An experimental and modeling study of the combustion of tetrahydrofuran.
Tran LS, et al.
Combustion and Flame, 162(5), 1899-1918 (2015)
Ilaria Massarelli et al.
European journal of medicinal chemistry, 44(9), 3658-3664 (2009-03-11)
A dataset comprising 55 chemicals with hepatocarcinogenic potency indices was collected from the Carcinogenic Potency Database with the aim of developing QSAR models enabling prediction of the above unwanted property for New Chemical Entities. The dataset was rationally split into
Anita Toulmin et al.
Journal of medicinal chemistry, 51(13), 3720-3730 (2008-06-19)
Partition coefficients were measured for 47 compounds in the hexadecane/water ( P hxd) and 1-octanol/water ( P oct) systems. Some types of hydrogen bond acceptor presented by these compounds to the partitioning systems are not well represented in the literature
Alfonso Pérez-Garrido et al.
Bioorganic & medicinal chemistry, 17(2), 896-904 (2008-12-06)
This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with beta-cyclodextrins (beta-CDs). Several different theoretical molecular descriptors, calculated solely from the molecular structure of the compounds under investigation
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