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34135

Supelco

Deepoxy-deoxynivalenol solution

~50 μg/mL in acetonitrile, analytical standard

Synonym(s):

3α,7α,15-Trihydroxy-trichothec-9,12-dien-8-one solution, DOM-1

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About This Item

Empirical Formula (Hill Notation):
C15H20O5
CAS Number:
88054-24-4
Molecular Weight:
280.32
EC Number:
200-835-2
MDL number:
MFCD07364056
UNSPSC Code:
85151701
PubChem Substance ID:
329754841
NACRES:
NA.24

grade

analytical standard

Quality Level

100

shelf life

limited shelf life, expiry date on the label

concentration

~50 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

SMILES string

CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)(C3=C)[C@@]2(CO)[C@H](O)C1=O

InChI

1S/C15H20O5/c1-7-4-10-15(6-16,13(19)11(7)18)14(3)5-9(17)12(20-10)8(14)2/h4,9-10,12-13,16-17,19H,2,5-6H2,1,3H3/t9-,10-,12+,13-,14+,15-/m1/s1

InChI key

ZACLXWTWERGCLX-MDUHGFIHSA-N

General description

Certan Vial
Deepoxy-deoxynivalenol is found to be a metabolite of the trichothecene mycotoxin deoxynivalenol, which can be generally found in swine.

Application

Deepoxy-deoxynivalenol solution may be used as internal standard in the determination of trichothecene mycotoxins present in baby foods, using high performance liquid chromatography coupled with mass spectrometry (HPLC/MS-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Analysis Note

purity : ≥92.5% (HPLC)

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F

Flash Point(C)

2 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK2478
BCCK2480
BCCK0497
BCCG3283
BCCF2702

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Barbara Novak et al.
Toxins, 10(4) (2018-04-12)
Deoxynivalenol (DON) is one of the most prevalent mycotoxins, contaminating cereals and cereal-derived products. Its derivative deepoxy-deoxynivalenol (DOM-1) is produced by certain bacteria, which either occur naturally or are supplemented in feed additive. DON-induced impairments in protein synthesis are particularly
Amin Sayyari et al.
Toxins, 10(12) (2018-12-07)
Deoxynivalenol (DON) contamination of feed may result in reduced growth, feed refusal, immunosuppression, and health problems in swine. Piglets can be exposed to DON via placenta before birth and via milk during lactation. The extent of early-life exposure of piglets
N De Zutter et al.
Scientific reports, 6, 38640-38640 (2016-12-09)
Biotransformation of mycotoxins in animals comprises phase I and phase II metabolisation reactions. For the trichothecene deoxynivalenol (DON), several phase II biotransformation reactions have been described resulting in DON-glutathiones, DON-glucuronides and DON-sulfates made by glutathione-S-transferases, uridine-diphosphoglucuronyl transferases and sulfotransferases, respectively.
Sandra Debevere et al.
Toxins, 12(6) (2020-06-25)
Ruminal microbiota of cattle are not able to detoxify all mycotoxins. In addition, detoxification can be hampered by adverse ruminal conditions (e.g., low ruminal pH). Hence, in the cattle husbandry, mycotoxin binders and modifiers could be used to prevent animal
Emma Gracia-Lor et al.
Journal of hazardous materials, 382, 121108-121108 (2019-09-07)
Mycotoxins are among the compounds of most concern for human health because of their common presence in food and their proven toxicity for human health. Human biomonitoring (HBM) studies, foodstuff analysis and dietary surveys are usually used to assess human
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