318604
Ammonium chloride-ammonium hydroxide buffer solution
in H2O
Synonym(s):
Ammonium Buffer Solution
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About This Item
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form
liquid
Quality Level
composition
NH4Cl, 1 wt. %
NH4OH, 4 wt. % (pH 10 to 11)
concentration
in H2O
pH
10-11
density
0.99 g/mL at 25 °C
SMILES string
N.N.O.Cl
InChI
1S/ClH.2H3N.H2O/h1H;2*1H3;1H2
InChI key
XEXFVRMLYUDDJY-UHFFFAOYSA-N
Application
Ammonium chloride-ammonium hydroxide buffer solution may be used to crystallize proteins.
Biochem/physiol Actions
Ammonium chloride is the salt component of ammonium chloride-ammonium hydroxide buffer system that completely inhibits the BVDV infection of MDBK cells when present at a concentration of 50 mM . Viruses treated with ammonium chloride (NH4Cl) results in loss of infectivity because it neutralizes the pH of endosome. Hence, viruses with low pH-dependent fusion activity became incapable to fuse their envelope with endosomal membrane.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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