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MSGVS2210

Millipore

Multiscreen® 96 well Plate, hydrophilic PVDF membrane

pore size 0.22 μm, sterile

Synonym(s):

96-Well Plate

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About This Item

UNSPSC Code:
41104923
eCl@ss:
32039006
NACRES:
NB.22

material

PVDF membrane (hydrophilic)
flat bottom wells
polystyrene

Quality Level

400

description

Sterile, clear 96-well filter plate with 0.22 um pore size Hydrophilic PVDF membrane for Receptor/Ligand Binding Assays, Protein Kinase/Phosphatase Precipitation Assays & Bead-based Assays.

sterility

sterile

product line

MultiScreen®

feature

hydrophilic
lid

manufacturer/tradename

MultiScreen®

parameter

50-250 μL sample volume (per well)

technique(s)

activity assay: suitable (protein kinase/phosphatase precipitation)
bead-based assay: suitable
ligand binding assay: suitable
receptor binding assay: suitable

filtration area

0.28 cm2

plate size

96 wells

well maximum volume

300 μL

working volume

50-250 μL

matrix

Durapore®

pore size

0.22 μm pore size

binding type

low binding surface

shipped in

ambient

Related Categories

General description

MultiScreen® plates are a reliable tool for advanced drug discovery and life science research. The MultiScreen HTS 96-well filtration plates are used to filter samples and perform entire procedures, from cell growth to scintillation counting within the same plate.

Application

MultiScreen® HTS GV Filter Plate, 0.22 μm, clear, sterile has been used:
  • in high throughput solubility and redissolution screening for antibody purification via combined PEG and zinc chloride precipitation
  • to filter Prochlorococcus cultures for hydrogen peroxide measurements
  • to filter the extracted sample for spectrometry analysis

Features and Benefits

  • The HTS Filter Plates are specifically developed for high-throughput use with automated work stations.
  • The rigid sidewalls improve handling and ample surfaces are provided for bar code labels.
  • The wells are individually sealed to prevent incubation crosstalk and the underdrain is removable for access to the filters.

Legal Information

Durapore is a registered trademark of Merck KGaA, Darmstadt, Germany
MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany

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Survival of Prochlorococcus in extended darkness
Coe A, et al.
Limnology and Oceanography, 61(4), 1375-1388 (2016)
Qin Gu et al.
Biotechnology progress, 36(6), e3041-e3041 (2020-06-26)
As upstream product titers increase, the downstream chromatographic capture step has become a significant "downstream bottleneck." Precipitation becomes more attractive under these conditions as the supersaturation driving force increases with the ever-increasing titer. In this study, two precipitating reagents with

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High density receptor-ligand binding assays

This web page shows how the MultiScreenHTS 384-well filter plate is used to perform receptor-ligand binding assays using the Human muscarinic M1 G-protein Coupled Receptor (GPCR) as a representative model system.

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