MABT37

Anti-Dentin sialoprotein Antibody, clone 2C12.3

clone 2C12.3, from mouse

• Synonym(s): Dentin sialophosphoprotein, Dentin phosphoprotein, Dentin phosphophoryn, DPP2.Dentin sialoprotein, DSP
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 2C12.3, monoclonal
• species reactivity: mouse, rat
• technique(s): immunohistochemistry: suitable
• isotype: IgG2bκ
• NCBI accession no.: NP_036922
• UniProt accession no.: Q62598
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: mouse ... Dspp(666279)

Description

General description

Dentin sialophosphoprotein (DSPP) is a protein of the extracellular matrix. It belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family. DSPP is found in teeth and bone and is primarily involved in biomineralization processes in these structures. This function may be facilitated by the interaction of DSPP with multiple protein targets including DMP1, BMP2, Runx2, and NF-Y. DSPP plays a central role in dentinogenesis.

Immunogen

Pure DSP isolated rat dentin

Application

Anti-Dentin sialoprotein, clone 2C12.3 detects levels of Dentin sialoprotein proteins & has been published & validated for use in IHC.

Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in rat mandibular tissue. (Baba, O., et al. (2004). Eur J Oral Sci. 112:163–170.)

Research Category
Cell Structure

Research Sub Category
Cytoskeleton

Quality

Evaluated by Immunohistochemistry in mouse and rat teeth tissues.

Immunohistochemistry Analysis: 1:250-1,000 dilution of this antibody detected Dentin sialophosphoprotein in mouse and rat teeth tissues.

Target description

68 kDa calculated. Uniprot describes 2 isoforms at 64 and 70 kDa

Physical form

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Mouse and rat teeth tissues

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable