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Key Documents

LP3

Sigma-Aldrich

High Density Lipoprotein, human

Synonym(s):

HDL

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About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.41

biological source

human

Quality Level

Assay

>95%

form

liquid

manufacturer/tradename

Chemicon®

General description

MOLECULAR WEIGHT:

175,000-360,000

DENSITY:

1.063 to 1.2 g/mL
Prepared by sequential flotation ultracentrifugation technique using KBr for density adjustments. HDL is the vehicle for reversed cholesterol transport and estrification, serving as a scavenger for free cholesterol during intravascular catabolism of lipoproteins. HDL levels are inversely correlated with coronary disease.
Product Source: Human plasma tested negative for HBsAg and HIV-I, HIV-II, HBc and Hepatitis C antibodies. All blood products should be treated as potentially infectious.

Linkage

Replaces: LP3-10MG

Physical form

Liquid in 150 mM NaCl, pH 7.4 with 0.01% EDTA. COMPOSITION: 55-45% lipid, 45-55% protein

Storage and Stability

Maintain at 2-8°C up to 3 months. Do not freeze. Freezing may cause denaturation.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ana C Alcalá et al.
Journal of virology, 96(5), e0166421-e0166421 (2022-01-06)
The dengue virus NS1 is a multifunctional protein that forms part of replication complexes. NS1 is also secreted, as a hexamer, to the extracellular milieu. Circulating NS1 has been associated with dengue pathogenesis by several mechanisms. Cell binding and internalization
Kai Liu et al.
Nature communications, 14(1), 4007-4007 (2023-07-07)
In terms of lipid nanoparticle (LNP) engineering, the relationship between particle composition, delivery efficacy, and the composition of the biocoronas that form around LNPs, is poorly understood. To explore this we analyze naturally efficacious biocorona compositions using an unbiased screening

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