369334

2-Guanidinoethylmercaptosuccinic Acid

Potent inhibitor of a carboxypeptidase B-like processing enzyme referred to as enkephalin convertase (K_i = 8.8 nM).

• Synonym(s): 2-Guanidinoethylmercaptosuccinic Acid, GEMSA
• CAS Number: 77482-44-1
• UNSPSC Code: 12352106
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥99% (TLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic)
• color: white
• solubility: water: soluble
• shipped in: ambient
• storage temp.: 2-8°C
• InChI: 1S/C7H13N3O4S/c8-7(9)10-1-2-15-4(6(13)14)3-5(11)12/h4H,1-3H2,(H,11,12)(H,13,14)(H4,8,9,10)
• InChI key: VKVCLXDFOQQABP-UHFFFAOYSA-N

Description

General description

Potent inhibitor of a carboxypeptidase B-like processing enzyme referred to as enkephalin convertase (K_i = 8.8 nM). Ideal for use in affinity chromatography of the enzyme.

Potent inhibitor of carboxypeptidase B-like processing enzyme referred to as enkephalin convertase (K_i = 8.8 nM). Ideal for use in affinity chromatography of the enzyme.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Enkephalin convertase

Product does not compete with ATP.

Reversible: no

Target K_i: 8.8 nM for enkephalin convertase

Warning

Toxicity: Standard Handling (A)

Other Notes

Bommer, M., et al. 1989. Brain Res. 492, 305.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable