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810285P

Avanti

TopFluor® Lyso PE

Avanti Polar Lipids 810285P, powder

Synonym(s):

1-(dipyrrometheneboron difluoride)undecanoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine

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About This Item

Empirical Formula (Hill Notation):
C29H47BF2N3O7P
CAS Number:
Molecular Weight:
629.48
UNSPSC Code:
12352211

Assay

>99% (LPE; may contain up to 10% of the 2-LPE isomer)

form

powder

packaging

pkg of 1 × 1 mg (810285P-1mg)

manufacturer/tradename

Avanti Polar Lipids 810285P

shipped in

dry ice

storage temp.

−20°C

General description

The phosphatidylethanolamine (PE) is a zwitterionic phospholipid. Its headgroup is provided with a phosphate, that is negatively charged and a free amine, that is positively charged. E is one of the widely distributed glycerophospholipid in eukaryotic cells.

Application

TopFluor® Lyso PE may be used in fluorescent substrate binding and competitive binding assays.

Biochem/physiol Actions

Phosphatidylethanolamine (PE) helps to activate factor (F)X and PT, thereby stimulating thrombosis. It serves as an anticoagulant. PE is essential for the surface expression of γ-aminobutyric acid type A receptors (GABAARs) in cultured neurons.

Packaging

5 mL Amber Glass Screw Cap Vial (810285P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lipid-protein interactions in membranes
Marsh D
Febs Letters, 268(2), 371-375 (1990)
Phosphatidylethanolamine metabolism in health and disease
International Review of Cell and Molecular Biology, 321(2), 29-88 (2016)
Antibodies and Diagnostic Tests in Antiphospholipid Syndrome
Systemic Lupus Erythematosus, 268(2), 495-501 (2016)
Proteostasis maintenance of Cys-loop receptors
Advances in Protein Chemistry and Structural Biology, 103(2), 1-23 (2016)
Substrate selectivity of lysophospholipid transporter LplT involved in membrane phospholipid remodeling in Escherichia coli
Lin Y, et al.
The Journal of Biological Chemistry, 291(5), 2136-2149 (2016)

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