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713791

Sigma-Aldrich

O,O′-Bis[2-(N-Succinimidyl-succinylamino)ethyl]polyethylene glycol

10,000

Synonym(s):

Polyethylene glycol, α,ω-Bis-NHS-PEG, Di(N-succinimidyl) PEG-diacid, PEG-bis(N-succinimidyl succinate)

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.22

form

lumps

mol wt

average Mn 10,000

reaction suitability

reagent type: cross-linking reagent

Ω-end

NHS ester

α-end

NHS ester

storage temp.

−20°C

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Articles

Circulatory half-life is a key success factor for new drugs. In this respect, PEGylation or PEG-ing—the modification of potential candidates ranging from non-peptidic small molecules to peptides and proteins, antibody fragments, aptamers, and saccharides or oligonucleotides with polyethylene glycol chains—offers numerous advantages.

The use of hydrogel-based biomaterials for the delivery and recruitment of cells to promote tissue regeneration in the body is of growing interest. This article discussed the application of hydrogels in cell delivery and tissue regeneration.

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