Skip to Content
Merck
All Photos(1)

Key Documents

More Documents

259772

Sigma-Aldrich

Chlorosulfonylacetyl chloride

95%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
ClSO2CH2COCl
CAS Number:
4025-77-8
Molecular Weight:
177.01
EC Number:
223-693-3
MDL number:
MFCD00007457
UNSPSC Code:
12352100
PubChem Substance ID:
24855434
NACRES:
NA.22

vapor pressure

0.06 mmHg ( 20 °C)

Quality Level

100

Assay

95%

form

liquid

refractive index

n20/D 1.493 (lit.)

bp

71-72 °C/1 mmHg (lit.)

density

1.669 g/mL at 25 °C (lit.)

SMILES string

ClC(=O)CS(Cl)(=O)=O

InChI

1S/C2H2Cl2O3S/c3-2(5)1-8(4,6)7/h1H2

InChI key

MCFSNYMQISXQTF-UHFFFAOYSA-N

Application

Chlorosulfonylacetyl chloride has been used in:
  • preparation of novel tricyclic benzothiazolo [2,3-c] thiadiazine antagonists of the platelet ADP receptor
  • N-terminal derivatization of peptides in rapid determination of peptide or protein sequences by matrix-assisted laser desorption ionization mass spectrometry

accessory

Product No.
Description
Pricing

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H314,H335

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

EUH014

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

R M Scarborough et al.
Bioorganic & medicinal chemistry letters, 11(14), 1805-1808 (2001-07-19)
Novel non-nucleoside tricyclic platelet ADP receptor (P2Y(12)) antagonists have been discovered that bind reversibly and with high affinity to the platelet receptor. Condensation of various 2-aminobenzothiazoles with chlorosulfonylacetyl chloride affords these novel tricyclic heterocycles, which are novel and unpredicted products
T Keough et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(13), 7131-7136 (1999-06-23)
A method has been developed for de novo peptide sequencing using matrix-assisted laser desorption ionization mass spectrometry. This method will facilitate biological studies that require rapid determination of peptide or protein sequences, e.g., determination of posttranslational modifications, identification of active

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service