SML3334
Ceefourin 1
≥95% (HPLC)
Synonym(s):
5-[(2-Benzothiazolylthio)methyl]-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione, Ceefourin-1
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About This Item
Empirical Formula (Hill Notation):
C11H10N4S3
CAS Number:
Molecular Weight:
294.42
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Quality Level
Assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
SMILES string
CN1C(CSC2=NC3=C(C=CC=C3)S2)=NNC1=S
Biochem/physiol Actions
Ceefourin 1 is a potent and highly selective MRP4 (Multidrug resistance protein 4) inhibitor that exhibits low cellular toxicity and high microsomal and acid stability. Ceefourin 1 inhibits PDAC (pancreatic ductal adenocarcinoma) cell proliferation through MRP4-dependent cAMP extrusion thereby activation of the cAMP/Epac/Rap1 signaling pathway.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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