SML0934

Enfuvirtide acetate salt

≥95% (HPLC)

• Synonym(s): T-20 acetate salt
• Empirical Formula (Hill Notation): C₂₀₄H₃₀₁N₅₁O₆₄ · xC₂H₄O₂
• CAS Number: 159519-65-0
• Molecular Weight: 4491.88 (free base basis)
• UNSPSC Code: 51111800
• NACRES: NA.77

Properties

• Assay: ≥95% (HPLC)
• form: powder
• storage condition: desiccated; protect from light
• color: white to off-white
• shipped in: wet ice
• storage temp.: −20°C

Description

Amino Acid Sequence

Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu- Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu- Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu- Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2 acetate

General description

Enfuvirtide acetate salt is a linear synthetic peptide made of 36 amino acids. It has an acetylated N-terminus and a carboxamide C-terminus. Enfuvirtide is catabolized with the help of proteolytic enzymes.

Biochem/physiol Actions

Enfuvirtide is an HIV fusion inhibitor used to patients with multi-drug resistant HIV. Enfuvirtide binds to gp41 preventing the creation of an entry pore for the HIV-1 virus.

Other Notes

Light sensitive

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable