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Key Documents

SAB5300233

Sigma-Aldrich

Monoclonal Anti-NQO1 antibody produced in mouse

clone 1A11, ascites fluid

Synonym(s):

DHQU, DIA4, DTD, NMOR1, QR1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

1A11, monoclonal

mol wt

31 kDa

species reactivity

human

technique(s)

direct ELISA: 1:10,000
flow cytometry: 1:200-1:400
western blot: 1:500-1:2,000

isotype

IgG1

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NQO1(1728)

Immunogen

Purified recombinant fragment of human NQO1 expressed in E.coli.
Mouse monoclonal antibody raised against NQO1

Physical form

Ascitic fluid containing 0.03% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Scott A Reisman et al.
Archives of dermatological research, 306(5), 447-454 (2013-12-24)
RTA 408 is a member of the synthetic oleanane triterpenoid class of compounds known to potently activate the cytoprotective transcription factor Nrf2. Because skin is constantly exposed to external oxidative stress, such as that from ultraviolet radiation, from chemical exposure
Junichi Sasaki et al.
Bioorganic & medicinal chemistry, 22(21), 6039-6046 (2014-10-05)
quinone oxidoreductase 1 (NQO1) is an obligate two-electron reductase and is highly expressed in many human solid cancers. Because NQO1 can be induced immediately after exposure to ionizing radiation, we aimed to develop an NQO1-targeted radiolabeled agent to establish a
Yasunobu Matsuda et al.
International journal of clinical and experimental pathology, 7(5), 2032-2043 (2014-06-27)
Hepatitis B virus X (HBX) protein plays a crucial role in carcinogenesis, but its mechanism is unclear. The involvement of ataxia telangiectasia mutated (ATM) kinase in the enhanced redox system was investigated by examining the phosphorylation level of ATM in
Naoki Mine et al.
Molecular cancer therapeutics, 13(9), 2215-2225 (2014-07-24)
CBP501 is an anticancer drug candidate that was investigated in two randomized phase II clinical trials for patients with nonsquamous non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma (MPM). CBP501 has been shown to have two mechanisms of action

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