SAB4502745

Anti-SFRP2 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): FRP-2, Frizzled-related protein 2, SARP-1, Secreted apoptosis-related protein 1, sFRP-2
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 33 kDa
• species reactivity: rat, mouse, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:5000; western blot: 1:500-1:1000
• NCBI accession no.: Q96HF1
• UniProt accession no.: Q96HF1
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... SFRP2(6423)

Description

General description

Anti-SFRP2 Antibody detects endogenous levels of total SFRP2 protein.

The SFRP2 (secreted frizzled related protein 2) gene is mapped to human chromosome 4q31.3. It is found to be expressed in sclerotome.

Immunogen

The antiserum was produced against synthesized peptide derived from human SFRP2.

Immunogen Range: 119-168

Biochem/physiol Actions

SFRP2 (secreted frizzled related protein 2) promotes phosphorylation and retards the expression of nuclear β-catenin and inhibits the canonical Wnt signaling pathway. SFRP2 is known to enhance osteogenic differentiation in mesenchymal stem cells.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable