Skip to Content
Merck
All Photos(1)

Key Documents

O5632

Sigma-Aldrich

Linoleic acid, conjugated methyl ester

Synonym(s):

CLA methyl ester, Octadecadienoic acid, conjugated, methyl ester

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
12352211
NACRES:
NA.25

biological source

plant (safflower)

Assay

≥99% (GC)

form

liquid

technique(s)

GC/MS: suitable
HPLC: suitable

impurities

≤1% Linoleic acid methyl ester

functional group

carboxylic acid
ester

lipid type

omega FAs

shipped in

ambient

storage temp.

−20°C

Related Categories

General description

Conjugated linoleic acid (CLA) describes the positional and geometric isomers of C18:2 fatty acids (FA) with a conjugated double bond. cis-9, trans-11 CLA are considered as the major isomers of CLA, based on in vitro experiments and animal studies in milk. The major source of CLA in human diet is the ruminant fat.

Application

Linoleic acid, conjugated methyl ester (CLA) has been used as a standard for the determination of isomers of CLA in milk samples by high performance liquid chromatography (HPLC), gas chromatography-mass spectrometry. It has also been used in the production of sn-1,3 diacyl glycerol.

Biochem/physiol Actions

Conjugated linoleic acid (CLA) isomers as supplements inhibit the growth of numerous human cancer cell lines. It also possesses immunostimulant properties, prevents diabetes and reduces atherosclerosis.

Other Notes

A mixture of cis- and trans-9,11- and -10,12-octadecadienoic acid methyl esters. Isomer ratio may vary from lot to lot.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ali Karabacak et al.
TheScientificWorldJournal, 2014, 821904-821904 (2014-02-14)
This study was conducted to compare fatty acid composition and content of conjugated linoleic acid (CLA) in different regions of sheep carcasses. Lambs of the Dağlıç breed were used for this purpose. Subsequent to a 68-day period of intensive fattening
Examination of the persistency of milk fatty acid composition responses to plant oils in cows given different basal diets, with particular emphasis on trans-C 18: 1 fatty acids and isomers of conjugated linoleic acid
Roy A, et al.
Animal Science Journal = Nihon Chikusan Gakkaiho, 82(4), 479-492 (2006)
M Coppa et al.
Journal of dairy science, 102(11), 10483-10499 (2019-09-10)
The aims of this work were to determine the effect of upland origin on milk composition when comparing similar lowland and upland production system and to highlight the factors responsible for the added value of upland milk from commercial farms.
Examination of the persistency of milk fatty acid composition responses to fish oil and sunflower oil in the diet of dairy cows
Shingfield KJ, et al.
Journal of Dairy Science, 89(2), 714-732 (2006)
Effect of incremental levels of sunflower-seed oil in the diet on ruminal lipid metabolism in lactating cows
Shingfield KJ, et al.
The British Journal of Nutrition, 99(5), 971-983 (2008)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service