M6514
3-(Trimethoxysilyl)propyl methacrylate
≥97%
Synonym(s):
Silane A174, [3-(Methacryloyloxy)propyl]trimethoxysilane
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About This Item
Linear Formula:
H2C=C(CH3)CO2(CH2)3Si(OCH3)3
CAS Number:
Molecular Weight:
248.35
Beilstein:
1952435
EC Number:
MDL number:
UNSPSC Code:
47101511
PubChem Substance ID:
NACRES:
NA.56
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![3-[Tris(trimethylsiloxy)silyl]propyl methacrylate contains MEHQ + HQ as stabilizer, 98%](/deepweb/assets/sigmaaldrich/product/structures/148/664/33ff5116-f264-4a64-824a-009c2ca5b2b3/640/33ff5116-f264-4a64-824a-009c2ca5b2b3.png)
Quality Level
Assay
≥97%
form
liquid
refractive index
n20/D 1.431 (lit.)
bp
190 °C (lit.)
density
1.045 g/mL at 25 °C (lit.)
storage temp.
2-8°C
SMILES string
CO[Si](CCCOC(=O)C(C)=C)(OC)OC
InChI
1S/C10H20O5Si/c1-9(2)10(11)15-7-6-8-16(12-3,13-4)14-5/h1,6-8H2,2-5H3
InChI key
XDLMVUHYZWKMMD-UHFFFAOYSA-N
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General description
3-(Trimethoxysilyl)propyl methacrylate (TMSPMA) is a hydrophobic monomer. The presence of an additional functional group of acrylate facilitates TMSPMA for grafting polymerization on plastic surfaces. 3-(Trimethoxysilyl)propyl methacrylate undergoes first-order kinetic polymerization to form polyTMSPMA, which is a moisture stable polymer.
Application
3-(Trimethoxysilyl)propyl methacrylate has been used in the following applications:
- Isoelectric focusing can lead to pH gradient formation resulting in the swelling or shrinking of gel casts. This can be prevented by using 3-(Trimethoxysilyl)propyl methacrylate to link polyacrylamide gels to glass plates covalently.
- In situ hybridization using 3-(Trimethoxysilyl)propyl methacrylate along with poly-L-lysine is a faster and durable method to attach cells, microscopic sections, and total organs to slides/other glass surfaces.
- 3-(Trimethoxysilyl)propyl methacrylate is also used in the preparation of organic/inorganic hybrid nanomaterials.
Packaging
A product Information sheet is supplied which describes procedures for using this product.
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Product No.
Description
Pricing
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
197.6 °F - closed cup
Flash Point(C)
92 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Sean Brahim et al.
Biomacromolecules, 4(5), 1224-1231 (2003-09-10)
An amphiphilic hydrogel of poly(2-hydroxyethyl methacrylate) cross-linked with tetraethyleneglycol diacrylate (TEGDA) was synthesized to contain the hydrophobic monomer 3-(trimethoxy-silyl) propyl methacrylate (PMA) and the pH-responsive, hydrophilic monomer N',N'-dimethylaminoethyl methacrylate (DMAEMA). The gels were separately loaded with two biomolecular probes, insulin
ATRP of 3-(triethoxysilyl)propyl methacrylate and preparation of ?stable? gelable block copolymers
Ming Xiong
European Polymer Journal, 44, 3835-3841 (2008)
M Aguadé et al.
Proceedings of the National Academy of Sciences of the United States of America, 91(11), 4658-4662 (1994-05-24)
Single-strand conformation polymorphism (SSCP) analysis followed by DNA sequencing of stratified sub-samples was used to survey DNA polymorphism in the su(s) and su(wa) regions in a natural population of Drosophila melanogaster. su(s) and su(wa) are located near the telomere of
Bozhen Zhang et al.
Journal of materials chemistry. B, 9(35), 7196-7204 (2021-07-23)
Label-free cell sorting devices are of great significance for biomedical research and clinical therapeutics. However, current platforms for label-free cell sorting cannot achieve continuity and selectivity simultaneously, resulting in complex steps and limited reliability. Here, an immunoaffinity-based cell catch-transport-release thermo-chemo-mechanical
Ke Liu et al.
Journal of colloid and interface science, 365(1), 289-295 (2011-10-04)
Thermoplastics have been increasingly used for fabricating microfluidic devices because of their low cost, mechanical/biocompatible attributes, and well-established manufacturing processes. However, there is sometimes a need to integrate such a device with components made from other materials such as polydimethylsiloxane
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