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H6411

Sigma-Aldrich

Monoclonal Anti-HIF-1α antibody produced in mouse

~1 mg/mL, clone OZ12, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-Hypoxia Inducible Factor 1, α subunit

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About This Item

MDL number:
MFCD01633488
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

200

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

OZ12, monoclonal

form

buffered aqueous solution

mol wt

antigen 120 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

immunoprecipitation (IP): 2 μg using 1 mg protein lysate
indirect immunofluorescence: 2 μg/mL

isotype

IgG1

UniProt accession no.

Q16665

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HIF1A(3091)

Immunogen

peptide corresponding to amino acids 530-826 of the human HIF-1α protein.

Physical form

Solution in phosphate buffered saline pH 7.4, containing 0.08% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Magdalena H Menhofer et al.
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Inhibiting angiogenesis is a major approach in tumour therapy. To combat angiogenesis, the tubulin cytoskeleton has emerged as an interesting target in many pre- and clinical studies. Contrarily, the actin cytoskeleton has been largely neglected as a potential drug target
Junhua Mao et al.
American journal of physiology. Renal physiology, 307(9), F1023-F1032 (2014-07-06)
Podocytes play a key role in the formation of cellular crescents in experimental and human diseases. However, the underlying mechanisms for podocytes in promoting crescent formation need further investigation. Here, we demonstrated that mammalian target of rapamycin complex 1 (mTORC1)

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