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Key Documents

B6775

Sigma-Aldrich

Anti-Human IgG1−Biotin antibody, Mouse monoclonal

clone 8c/6-39, purified from hybridoma cell culture

Synonym(s):

Monoclonal Anti-Human IgG1 (Fc specific), Anti Human IgG1 - Monoclonal Anti-Human IgG1-Biotin antibody produced in mouse, Anti Human Igg1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

mouse

Quality Level

200

conjugate

biotin conjugate

antibody form

purified from hybridoma cell culture

antibody product type

secondary antibodies

clone

8c/6-39, monoclonal

form

buffered aqueous solution

technique(s)

direct ELISA: 1:1,000

isotype

IgG2a

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

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General description

Human IgGs are glycoprotein antibodies that contain two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4. These antibodies regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders
Monoclonal Anti-Human IgG1-Biotin antibody is specific for an epitope in the Fc region of the human IgG1. The product does not react with human IgG2, IgG3, or IgG4. This antibody clone (HP6019 clone) has been recognized as a useful human IgG1 specificity standard in the WHO/IUIS study .
The antibody is specific for the Fc portion of human IgG1 and is non-reactive with other IgG subclasses. This clone, also described as HP-6091, was found to exhibit a valuable profile of reactivity and specificity for human IgG1 by the IUIS/WHO study.

Immunogen

Fc fragment of myeloma Human IgG

Application

Monoclonal Anti-Human IgG1-Biotin antibody is suitable for use in immunoblot. The product can also be used for direct ELISA (1:1,000).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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