251755

Osmium tetroxide solution

4 wt. % in H₂O

• Linear Formula: OsO₄
• CAS Number: 20816-12-0
• Molecular Weight: 254.23
• MDL number: MFCD00011150
• UNSPSC Code: 12352303
• PubChem Substance ID: 329752782
• NACRES: NA.21

Properties

• vapor pressure: 1.23 psi ( 20 °C); 3.55 psi ( 55 °C)
• Quality Level: 100
• form: liquid
• reaction suitability: reagent type: oxidant
• concentration: 3.5-4.5% (OsO₄); 4 wt. % in H₂O
• density: 1.0 g/mL at 20 °C; 1.04 g/mL at 25 °C
• storage temp.: 2-8°C
• SMILES string: O=[Os](=O)(=O)=O
• InChI: 1S/4O.Os
• InChI key: VUVGYHUDAICLFK-UHFFFAOYSA-N

Description

General description

OsO₄ (4wt% in H₂O) is widely employed in organic synthesis especially for hydroxylation reactions. Additionally, it is also involved in the oxidative cleavage of alkenes.

Application

• In situ X-ray-assisted electron microscopy staining for large biological samples.: This study explores the use of osmium tetroxide solution for X-ray-assisted electron microscopy staining, enhancing the visualization of large biological samples (Ströh et al., 2022).


• Application of the electron microscope to the cytochemical peroxidase reaction in salamander leukocytes.: The use of osmium tetroxide solution in electron microscopy enhances the cytochemical analysis of peroxidase reactions in salamander leukocytes, providing clear and detailed images (MITSUI, 1960).

Safety Information

• Pictograms: GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H302 + H332,H310,H315,H318
• Precautionary Statements: P262 - P280 - P301 + P312 - P302 + P352 + P310 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
• Storage Class Code: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable