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228710

Sigma-Aldrich

Sodium nitroferricyanide(III) dihydrate

ACS reagent, ≥99%

Synonym(s):

Nitroprusside sodium, SNP, Sodium nitroprusside, Sodium pentacyanonitrosylferrate

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About This Item

Linear Formula:
Na2[Fe(CN)5NO] · 2H2O
CAS Number:
13755-38-9
Molecular Weight:
297.95
EC Number:
238-373-9
MDL number:
MFCD00149192
UNSPSC Code:
12352300
PubChem Substance ID:
329752353
NACRES:
NA.21

grade

ACS reagent

Quality Level

200

Assay

≥99%

form

crystals

reaction suitability

reagent type: catalyst
core: iron

impurities

≤0.01% insolubles

anion traces

chloride (Cl-): ≤0.02%
sulfate (SO42-): passes test (lim. ~1%)

SMILES string

[Na+].[Na+].[H]O[H].[H]O[H].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N

InChI

1S/5CN.Fe.NO.2Na.2H2O/c5*1-2;;1-2;;;;/h;;;;;;;;;2*1H2/q;;;;;2*-1;2*+1;;

InChI key

OIRZWVYIQXBRFC-UHFFFAOYSA-N

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General description

Sodium nitroferricyanide(III) dihydrate (sodium nitroprusside dihydrate, SNP) is a dihydrate form of sodium nitroprusside. It is comprised of ferrous iron complexed with nitric oxide (NO) and five cyanide ions. It serves as a donor of nitric oxide.

Application

Sodium nitroferricyanide(III) dihydrate can be used as a reagent to produce nitric oxide radicals (NO) via UV radiation-induced photolysis. These radicals are employed for the construction of amino acid-based supramolecular hydrogels, which find potential applications in disease diagnosis and therapy including bioimaging, bio-detection, therapeutic delivery, and tissue engineering. Additionally, SNP also serves as a catalyst in the Phenate Method for the quantitative measurement of ammonia in water samples.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Anal. Profiles Drug Subst., 6, 487-513 (1977)
Polyhedron, 22, 2527-2535 (2003)
Oluwatobiloba Osikoya et al.
The Journal of physiology, 597(15), 3833-3852 (2019-06-06)
In vivo, uterine perivascular adipose tissue (PVAT) potentiates uterine artery blood flow in pregnant rats, although not in non-pregnant rats. In isolated preparations, uterine PVAT has pro-contractile and anti-dilatory effects on uterine arteries. Pregnancy induces changes in uterine arteries that
Bas van den Bogaard et al.
American journal of hypertension, 26(4), 574-579 (2013-03-08)
Sodium nitroprusside (SNP) and labetalol are recommended for the immediate treatment of malignant hypertension. Both are intravenous agents but have different effects on systemic hemodynamics, and may have differential effects on pulse-wave reflection and pulse-pressure amplification, with consequences for peripheral
A Moerman et al.
British journal of anaesthesia, 111(4), 619-626 (2013-06-07)
Although both pressure and flow are considered important determinants of regional organ perfusion, the relative importance of each is less established. The aim of the present study was to evaluate the impact of variations in flow, pressure, or both on
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