T0254

L-Tryptophan

reagent grade, ≥98% (HPLC)

• Synonym(s): (S)-2-Amino-3-(3-indolyl)propionic acid, L-α-Amino-3-indolepropionic acid
• Empirical Formula (Hill Notation): C₁₁H₁₂N₂O₂
• CAS Number: 73-22-3
• Molecular Weight: 204.23
• Beilstein: 86197
• EC Number: 200-795-6
• MDL number: MFCD00064340
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24278135
• NACRES: NA.26

Properties

• grade: reagent grade
• Quality Level: 200
• Assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• mp: 280-285 °C (dec.) (lit.)
• solubility: 0.5 M HCl: 50 mg/mL
• application(s): cell analysis
• SMILES string: N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
• InChI: 1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
• InChI key: QIVBCDIJIAJPQS-VIFPVBQESA-N
• Gene Information: human ... TDO2(6999) , TPH1(7166) , TPH2(121278)

Description

Application

L-tryptophan has been used for the isolation of bone marrow–derived neutrophils. It has also been used to identify the use of Raman microscopy as a tool to study the network of neurons in pathologically normal retina.

Biochem/physiol Actions

Tryptophan (Trp) is a heterocyclic, essential amino acid associated with growth, reproduction and immunity. Increased availability of tryptophan is necessary for the regulation of mood, cognition and behavior. The uptake of tryptophan by the brain depends on the plasma ratio of Trp to all of the other large neutral amino acids. Higher the ratio, greater is the Trp uptake.

Other Notes

Amino acid precursor of serotonin and melatonin

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves