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PHR1433

Supelco

Ascorbyl Glucoside

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Ascorbyl Glucoside

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About This Item

Empirical Formula (Hill Notation):
C12H18O11
CAS Number:
129499-78-1
Molecular Weight:
338.26
MDL number:
MFCD23701380
UNSPSC Code:
41116107
PubChem Substance ID:
329822597
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

API family

ascorbyl glucoside

form

solid

CofA

current certificate can be downloaded

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(C1=O)O[C@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO

InChI

1S/C12H18O11/c13-1-3(15)9-8(19)10(11(20)22-9)23-12-7(18)6(17)5(16)4(2-14)21-12/h3-7,9,12-19H,1-2H2/t3-,4+,5+,6-,7+,9+,12+/m0/s1

InChI key

MLSJBGYKDYSOAE-DCWMUDTNSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ascorbyl Glucoside is used to protect skin from exposure to UV rays.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA2741 in the slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAC4839
LRAA9214
LRAA2741

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Kenji Ichiyama et al.
Immunology letters, 122(2), 219-226 (2009-02-10)
The stable ascorbic acid derivative 2-O-alpha-D-glucopyranosyl-L-ascorbic acid (AA-2G) was used to investigate the role of ascorbic acid (AA) in B cell differentiation in vitro. AA-2G is stable in a solution unlike AA but is hydrolyzed by cellular alpha-glucosidase to release
Chien-Yu Hsiao et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 38(8), 1284-1293 (2012-06-08)
Topical treatment with vitamin C has been used to treat photoaged skin and as a skin whitener, but no standard procedure exists for percutaneous delivery. To compare skin histology and the permeation of ascorbic acid 2-glucoside (AA2G) after fractional and
Akihiro Tai et al.
Bioscience, biotechnology, and biochemistry, 74(9), 1969-1971 (2010-09-14)
6-O-dodecanoyl-2-O-α-D-glucopyranosyl-L-ascorbic acid (6-sDode-AA-2G) was synthesized from 2-O-α-D-glucopyranosyl-L-ascorbic acid and vinyl laurate with a protease from Bacillus subtilis in 30% dimethylformamide (DMF)/dioxane with a low water content. The addition of 3% (v/v) water to DMF/dioxane dramatically enhanced the 6-sDode-AA-2G synthesis. The
Ruizhi Han et al.
Applied microbiology and biotechnology, 97(13), 5851-5860 (2012-11-07)
In this work, the site-saturation engineering of lysine 47 in cyclodextrin glycosyltransferase (CGTase) from Paenibacillus macerans was conducted to improve the specificity of CGTase towards maltodextrin, which can be used as a cheap and easily soluble glycosyl donor for the
Sadako Nakamura et al.
Nutrition (Burbank, Los Angeles County, Calif.), 25(6), 686-691 (2009-02-24)
2-O-alpha-D-glucopyranosyl-L-ascorbic acid (AA2G) is a stable glycoside, but its conversion to bioavailable ascorbic acid (AsA) in humans remains unknown. The aim of this study was to clarify that AA2G is hydrolyzed by human intestinal maltase and AA2G by oral ingestion
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