FCMAB255F

Milli-Mark^® Anti-Mouse IL-17 FITC Antibody, clone TC11-18H10.1

clone TC11-18H10.1, Milli-Mark^®, from rat

• Synonym(s): Cytotoxic T-lymphocyte-associated antigen 8
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rat
• conjugate: FITC conjugate
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• clone: TC11-18H10.1, monoclonal
• species reactivity: mouse
• manufacturer/tradename: Milli-Mark^®
• technique(s): flow cytometry: suitable
• isotype: IgG1κ
• NCBI accession no.: NP_034682
• UniProt accession no.: Q62386
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: mouse ... Il17A(16171)

Description

General description

IL17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL1beta, IL6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL17are significantly increased and may contribute to bone destruction.

Specificity

Antibody recognizes Interleukin-17A.

Immunogen

Recombinant protein corresponding to mouse Il17a

Application

Milli-Mark Anti-Mouse IL-17 FITC Antibody, clone TC11-18H10.1 detects level of Mouse IL-17 & has been published & validated for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunological Signaling

Quality

Evaluated by flow cytometry using stimulated EL-4 cells

Target description

17 kDa Calculated

Physical form

Antigen Affinity Purified

Purified rat monoclonal IgG1κ conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Storage and Stability

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Analysis Note

Control
PMA and Ionomycin stimulated EL-4 cells.

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable