474500

4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide

Ultrasensitive, fluorogenic substrate for assay of N-acetyl-α-D-glucosaminidase. Can be used to test for Sanfilippo syndrome B.

• Synonym(s): 4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide, 4-Methylumbelliferyl-2-acetamido-2-deoxy-α-D-glucopyranoside
• Empirical Formula (Hill Notation): C₁₈H₂₁NO₈
• CAS Number: 80265-04-9
• Molecular Weight: 379.36
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated; protect from light
• impurities: <0.05% 4-methylumbelliferone; <0.2% β-anomer
• color: white
• solubility: DMF: soluble; DMSO: soluble
• shipped in: ambient
• storage temp.: 10-30°C
• InChI: 1S/C18H21NO8/c1-8-5-14(22)26-12-6-10(3-4-11(8)12)25-18-15(19-9(2)21)17(24)16(23)13(7-20)27-18/h3-6,13,15-18,20,23-24H,7H2,1-2H3,(H,19,21)/t13-,15-,16-,17-,18+/m1/s1
• InChI key: QCTHLCFVVACBSA-FGTAOJJYSA-N

Description

General description

Ultrasensitive, fluorogenic substrate for assay of N-acetyl-α-D-glucosaminidase. Can be used to test for Sanfilippo B syndrome. Excitation maximum: 360 nm; emission maximum: 440 nm.

Ultrasensitive, fluorogenic substrate for assay of N-acetyl-α-D-glucosaminidase. Can be used to test for Sanfilippo syndrome B.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Unstable in solution; reconstitute just prior to use.

Analysis Note

single spot by TLC

Other Notes

Marsh, J., and Fensom, A.H. 1985. Clin. Genet.27, 258.
Chow, P., and Weissmann, B. 1981. Carbohydr. Res. 96, 87.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable