1.00514

Perchloric acid

70%, for analysis (max. 0.0000005% Hg) EMSURE^® ACS,ISO,Reag. Ph Eur

• Synonym(s): Perchloric acid, PCA
• Linear Formula: HClO₄
• CAS Number: 7601-90-3
• Molecular Weight: 100.46
• MDL number: MFCD00011325
• UNSPSC Code: 12352301
• NACRES: NA.21

Properties

• product name: Perchloric acid 70%, for analysis (max. 0.0000005% Hg) EMSURE^® ACS,ISO,Reag. Ph Eur
• grade: ACS reagent
• Quality Level: 300
• Agency: reag. ISO; reag. Ph. Eur.
• product line: EMSURE^®
• form: liquid
• concentration: 70.0-72.0% HClO₄
• impurities: ≤0.005 ppm Hg (Mercury); ≤0.02 ppm Ba (Barium); ≤0.02 ppm Be (Beryllium); ≤0.02 ppm Li (Lithium); ≤0.02 ppm Mn (Manganese); ≤0.02 ppm Sr (Strontium); ≤0.05 ppm Al (Aluminium); ≤0.05 ppm As (Arsenic); ≤0.05 ppm Cd (Cadmium); ≤0.05 ppm Co (Cobalt); ≤0.05 ppm Ge (Germanium); ≤0.05 ppm Mo (Molybdenum); ≤0.05 ppm Pb (Lead); ≤0.05 ppm Tl (Thallium); ≤0.05 ppm V (Vanadium); ≤0.1 ppm Ag (Silver); ≤0.1 ppm Bi (Bismuth); ≤0.1 ppm Cu (Copper); ≤0.1 ppm K (Potassium); ≤0.1 ppm Ni (Nickel); ≤0.1 ppm Ti (Titanium); ≤0.1 ppm Zn (Zinc); ≤0.1 ppm Zr (Zirconium); ≤0.5 ppm Ca (Calcium); ≤0.5 ppm Free chlorine; ≤0.5 ppm Mg (Magnesium); ≤0.5 ppm Na (Sodium); ≤1 ppm Heavy metals (as Pb); ≤1.0 ppm Fe (Iron); ≤10 ppm Chlorate (ClO₃); ≤10 ppm Sulfate (SO₄); ≤10 ppm Total nitrogen (N); ≤3 ppm Chloride (Cl); ≤5 ppm Phosphate and Silicate (as SiO₂)
• ign. residue: ≤30 ppm (as sulfate)
• SMILES string: OCl(=O)(=O)=O
• color: APHA: ≤10
• bp: 198.7 °C/1013 hPa
• mp: -18 °C
• density: 1.68 g/cm³ at 20 °C
• storage temp.: 15-25°C
• InChI: 1S/ClHO4/c2-1(3,4)5/h(H,2,3,4,5)
• InChI key: VLTRZXGMWDSKGL-UHFFFAOYSA-N

Description

Application

• Development and validation of an HPLC method for the determination of vancomycin in human plasma and its comparison with an immunoassay (PETINIA).: This study developed and validated an HPLC method using 70% perchloric acid for the determination of vancomycin in human plasma, highlighting its application in analytical chemistry for therapeutic drug monitoring (Usman and Hempel, 2016).
• Determination of sunscreen agents in cosmetic products by reversed-phase high performance liquid chromatography.: The research utilized 70% perchloric acid in the sample preparation process, demonstrating its efficacy in the analysis of cosmetic products for regulatory and quality control purposes (Yao et al., 1998).
• Colorimetric determination of hydroxyurea in human serum using high-performance liquid chromatography.: This article describes a colorimetric method involving 70% perchloric acid for sample preparation, which is crucial in clinical chemistry for monitoring hydroxyurea levels in patients (Manouilov et al., 1998).
• Application of biological samples treated by wet-digested mineralization to cation-exchange high-performance liquid chromatography with post-column reaction by 4-(2-pyridylazo)-resorcinol.: This study details the use of 70% perchloric acid in the mineralization of biological samples, essential for accurate trace metal analysis in biological research (Sudo et al., 1991).
• Colorimetric micromethods for glutaraldehyde determination by means of phenol and sulfuric acid or phenol and perchloric acid.: The research presents a micromethod utilizing 70% perchloric acid for the colorimetric determination of glutaraldehyde, applicable in biochemical and industrial laboratories for safety and quality assessments (Boratynski and Zal, 1990).

Analysis Note

Assay (acidimetric): 70.0 - 72.0 %
Color: ≤ 10 Hazen
Chlorate (ClO₃): ≤ 10 ppm
Chloride (Cl): ≤ 3 ppm
Free chlorine: ≤ 0.5 ppm
Phosphate and Silicate (as SiO₂): ≤ 5 ppm
Sulfate (SO₄): ≤ 10 ppm
Total nitrogen (N): ≤ 10 ppm
Heavy metals (as Pb): ≤ 1 ppm
Ag (Silver): ≤ 0.1 ppm
Al (Aluminium): ≤ 0.05 ppm
As (Arsenic): ≤ 0.05 ppm
Ba (Barium): ≤ 0.02 ppm
Be (Beryllium): ≤ 0.02 ppm
Bi (Bismuth): ≤ 0.1 ppm
Ca (Calcium): ≤ 0.5 ppm
Cd (Cadmium): ≤ 0.05 ppm
Co (Cobalt): ≤ 0.05 ppm
Cu (Copper): ≤ 0.1 ppm
Fe (Iron): ≤ 1.0 ppm
Ge (Germanium): ≤ 0.05 ppm
Hg (Mercury): ≤ 0.005 ppm
K (Potassium): ≤ 0.1 ppm
Li (Lithium): ≤ 0.02 ppm
Mg (Magnesium): ≤ 0.5 ppm
Mn (Manganese): ≤ 0.02 ppm
Mo (Molybdenum): ≤ 0.05 ppm
Na (Sodium): ≤ 0.5 ppm
Ni (Nickel): ≤ 0.1 ppm
Pb (Lead): ≤ 0.05 ppm
Sr (Strontium): ≤ 0.02 ppm
Ti (Titanium): ≤ 0.1 ppm
Tl (Thallium): ≤ 0.05 ppm
V (Vanadium): ≤ 0.05 ppm
Zn (Zinc): ≤ 0.1 ppm
Zr (Zirconium): ≤ 0.1 ppm
Residue on ignition (as sulfate): ≤ 30 ppm
Identity: passes test
Density (d 20/20): approx. 1.7
Conform to ACS, ISO, Reag.Ph Eur.

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS03,GHS05,GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H271 - H290 - H302 - H314 - H373
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Ox. Liq. 1 - Skin Corr. 1A - STOT RE 2
• Target Organs: Thyroid
• Storage Class Code: 5.1A - Strongly oxidizing hazardous materials
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable