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ALD00532

Sigma-Aldrich

Serine Hydrolase Inhibitor-11

95%

Synonym(s):

Piperidin-1-yl(1H-pyrazol-1-yl)methanone, SHI-11

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About This Item

Empirical Formula (Hill Notation):
C9H13N3O
CAS Number:
1622426-14-5
Molecular Weight:
179.22
UNSPSC Code:
12352200
PubChem Substance ID:
329772708
NACRES:
NA.22

Quality Level

100

Assay

95%

form

liquid

SMILES string

O=C(N1CCCCC1)N2N=CC=C2

InChI

1S/C9H13N3O/c13-9(12-8-4-5-10-12)11-6-2-1-3-7-11/h4-5,8H,1-3,6-7H2

InChI key

RVUWRYIKKXZWFA-UHFFFAOYSA-N

Application

Serine hydrolase inhibitors are small molecule fragments that react in vitro with the serine hydrolase class of proteins. They are amenable to further modification to create novel inhibitors of this class of protein.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Katerina Otrubova et al.
Bioorganic & medicinal chemistry letters, 24(16), 3807-3813 (2014-07-20)
Two libraries of modestly reactive ureas containing either electron-deficient acyl anilines or acyl pyrazoles were prepared and are reported as screening libraries for candidate serine hydrolase inhibitors. Within each library is a small but powerful subset of compounds that serve

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