901699
3-Mercaptopropanyl-N-hydroxysuccinimide ester
>95%
Synonym(s):
NHS ester
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About This Item
Empirical Formula (Hill Notation):
C7H9NO4S
CAS Number:
Molecular Weight:
203.22
MDL number:
UNSPSC Code:
12352005
NACRES:
NA.23
Assay
>95%
form
solid or liquid
reaction suitability
reagent type: linker
color
colorless to yellow
functional group
NHS ester
thiol
storage temp.
2-8°C
SMILES string
SCCC(ON1C(CCC1=O)=O)=O
InChI
1S/C7H9NO4S/c9-5-1-2-6(10)8(5)12-7(11)3-4-13/h13H,1-4H2
InChI key
UTBOEPMMEANMPS-UHFFFAOYSA-N
Application
3-Mercaptopropanyl-N-hydroxysuccinimide ester is an aliphatic, heterobifunctional crosslinking reagent. Due to the functional groups, this material can be used in a multitude of applications, such as the synthesis of protien-polymer conjugates and the synthesis of functionalized quantum dots. In addition to use as a crosslinking agent, this material can also be used to install functional groups post-polymerization. The terminal N-hydroxysuccinimide (NHS) ester can react with amines while the terminal thiol can react with thiols, alkenes, and alkynes. The free thiol can also be used to form self-assembled monolayers (SAMs) on gold surfaces.
3-Mercaptopropanyl-N-hydroxysuccinimide ester can be used in the synthesis of diaminobutane (DAB) based dendrimers for the formation of an ultrafiltration membrane for the removal of heavy metals.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Flam. Liq. 3
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
110.0 °F
Flash Point(C)
43.33 °C
Certificates of Analysis (COA)
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