526169

1,8-Dimethyl-1,4,8,11-tetraazacyclotetradecane

• Synonym(s): 1,8-Dimethylcyclam
• Empirical Formula (Hill Notation): C₁₂H₂₈N₄
• CAS Number: 214078-92-9
• Molecular Weight: 228.38
• MDL number: MFCD03427012
• UNSPSC Code: 12352100
• PubChem Substance ID: 24874539
• NACRES: NA.22

Properties

• refractive index: n20/D 1.4940 (lit.)
• Quality Level: 100
• bp: 98-99 °C (lit.)
• density: 0.944 g/mL at 25 °C (lit.)
• SMILES string: CN1CCCNCCN(C)CCCNCC1
• InChI: 1S/C12H28N4/c1-15-9-3-5-14-8-12-16(2)10-4-6-13-7-11-15/h13-14H,3-12H2,1-2H3
• InChI key: BNLDMZVBFXARKJ-UHFFFAOYSA-N

Description

General description

1,8-Dimethyl-1,4,8,11-tetraazacyclotetradecane is a heterocyclic building block.

Application

1,8-Dimethyl-1,4,8,11-tetraazacyclotetradecane may be used as a precursor for the synthesis of `trans′-difunctionalized derivatives. It may also be used in the synthesis of 4,11-bis(N-pyren-1-yl-acetamide)-1,8-dimethyl-1,4,8,11-tetraazacyclotetradecane.

Reactant for:

• Ferromagnetic coupling of copper(II) and nickel(II) complexes
• Preparation of cyclam bridged dinuclear platinum(II) complex as an antitumor agent
• Preparation of dimethylcyclam based fluoroionophore having Hg²⁺- and Cd²⁺-selective signaling behaviors

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 195.1 °F - closed cup
• Flash Point(C): 90.6 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves