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Sigma-Aldrich

Iminodiacetic acid

98%, for peptide synthesis

Synonym(s):

2,2′-Azanediyldiacetic acid, Diglycine, IMDA

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About This Item

Linear Formula:
HN(CH2COOH)2
CAS Number:
142-73-4
Molecular Weight:
133.10
Beilstein:
878499
EC Number:
205-555-4
MDL number:
MFCD00004280
UNSPSC Code:
12352106
PubChem Substance ID:
24853159
NACRES:
NA.22

product name

Iminodiacetic acid, 98%

Assay

98%

form

solid

mp

243 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

OC(=O)CNCC(O)=O

InChI

1S/C4H7NO4/c6-3(7)1-5-2-4(8)9/h5H,1-2H2,(H,6,7)(H,8,9)

InChI key

NBZBKCUXIYYUSX-UHFFFAOYSA-N

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General description

Iminodiacetic acid is a versatile chelating agent widely used in metal extraction and waste water treatment.

Application

Iminodiacetic acid can be used:
  • In the preparation of iminodiacetic acid (IDA)-type adsorbent for protein purification.
  • As a catalyst along with iron (FeCl3) complexes for methyl methacrylate (MMA) polymerization.
  • In the preparation of chelating resins with glycidyl methacrylate for the selective removal and recovery of metal ions from industrial waste water.
  • As a reagent for the preparation of pinene-derived iminodiacetic acid (PIDA), which is in turn used as a ligand for the synthesis of diastereoselective oxiranyl C(sp3) boronates from the corresponding olefins.
  • In the surface functionalization of multi-walled carbon nanotubes (MWCNTs) which is further utilized as a sorbent for the separation of heavy metal ions.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Preparation of iminodiacetic acid functionalized multi-walled carbon nanotubes and its application as sorbent for separation and preconcentration of heavy metal ions
Wang J, et al.
Journal of Hazardous Materials, 186(2-3), 1985-1992 (2011)
Chromatographic separation of proteins on metal immobilized iminodiacetic acid-bound molded monolithic rods of macroporous poly (glycidyl methacrylate-co-ethylene dimethacrylate)
Luo Q, et al.
Journal of Chromatography A, 926(2), 255-264 (2001)
AGET ATRP of methyl methacrylate catalyzed by FeCl3/iminodiacetic acid in the presence of air
Zhang L, et al.
Polymer, 49(13-14), 3054-3059 (2008)
Synthesis of chelating resins with iminodiacetic acid and its wastewater treatment application
Wang C-C, et al.
Journal of Applied Polymer Science, 84(7), 1353-1362 (2002)
Hong-Ming Yang et al.
Analytical biochemistry, 432(2), 134-138 (2012-10-03)
Highly efficient protein immobilization is extremely crucial for solid-phase immunoassays. We present a strategy for oriented immobilization of functionally intact immunoglobulin G (IgG) on a polystyrene microtiter plate via iminodiacetic acid (IDA)-Ni(2+) and ZZ-His protein interaction. We immobilized a ZZ-EAP
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