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166952

Sigma-Aldrich

2-Hydroxybenzyl alcohol

99%

Synonym(s):

Salicyl alcohol, Saligenin

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About This Item

Linear Formula:
HOC6H4CH2OH
CAS Number:
90-01-7
Molecular Weight:
124.14
Beilstein:
1907195
EC Number:
201-960-5
MDL number:
MFCD00004617
UNSPSC Code:
12352100
PubChem Substance ID:
24850189
NACRES:
NA.22

Assay

99%

form

solid

mp

83-85 °C (lit.)

solubility

ethanol: soluble 5%, clear to very slightly hazy, colorless to light yellow

SMILES string

OCc1ccccc1O

InChI

1S/C7H8O2/c8-5-6-3-1-2-4-7(6)9/h1-4,8-9H,5H2

InChI key

CQRYARSYNCAZFO-UHFFFAOYSA-N

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General description

2-Hydroxybenzyl alcohol participates in the selective ring opening reaction of 4H-1,3,2-benzodioxasilines.

2-Hydroxybenzyl alcohol can be used as a coupling reagent to synthesize O-heterocycles.

Application

2-Hydroxybenzyl alcohol was used in gastrodin production via biotransformation by cultured cells of Aspergillus foetidus and Penicillium cyclopium.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Selective ring opening of 4H-1, 3, 2-benzodioxasiline twin monomers.
Kempe P, et al.
New. J. Chem., 35(12), 2735-2739 (2011)
Linlin Fan et al.
Applied biochemistry and biotechnology, 170(1), 138-148 (2013-03-14)
The objective of this work was to take advantage of the resting cells of suitable fungus as an in vitro model to prepare gastrodin from p-2-hydroxybenzyl alcohol (HBA), which mainly exists in the metabolites of the plant Gastrodia elata Blume.
Per Borgquist et al.
Journal of controlled release : official journal of the Controlled Release Society, 113(3), 216-225 (2006-06-27)
A model for simulating the drug release from a swelling and dissolving polymer tablet is presented and verified to data. The model is based on a mechanistic approach, and it can therefore be employed to study the sensitivity of true
Mariagrazia Marucci et al.
Journal of controlled release : official journal of the Controlled Release Society, 114(3), 369-380 (2006-08-15)
In this work, Electronic Speckle Pattern Interferometry (ESPI) is presented as a non-invasive tool to study drug transport in controlled release systems. ESPI is shown to be a feasible tool to measure drug film permeability via comparison with an ordinary
Carmen Michalski et al.
The Journal of biological chemistry, 283(28), 19219-19228 (2008-05-17)
Salicyl alcohol oxidase is an extracellular enzyme that occurs in glandular reservoirs of chrysomelid leaf beetle larvae and catalyzes the formation of salicylaldehyde, a volatile deterrent used by the larvae against predators. Salicyl alcohol is the hydrolysis product of salicin
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