SMB01048

Uzarin

≥90% (LC/MS-ELSD)

• Synonym(s): (3beta,5alpha)-3-((6-O-beta-D -glucopyranosyl-beta-D -glucopyranosyl)oxy)-14-hydroxycard-20(22)-enolide, Uzarigenin 3-β-sophoroside
• Empirical Formula (Hill Notation): C₃₅H₅₄O₁₄
• CAS Number: 20231-81-6
• Molecular Weight: 698.79
• UNSPSC Code: 12352205
• NACRES: NA.25

Properties

• biological source: plant
• Assay: ≥90% (LC/MS-ELSD)
• form: solid
• mol wt: 698.79
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: −20°C
• InChI: 1S/C35H54O14/c1-33-8-5-18(46-32-30(28(42)26(40)23(14-37)48-32)49-31-29(43)27(41)25(39)22(13-36)47-31)12-17(33)3-4-21-20(33)6-9-34(2)19(7-10-35(21,34)44)16-11-24(38)45-15-16/h11,17-23,25-32,36-37,39-44H,3-10,12-15H2,1-2H3/t17-,18-,19+,20-,21+,22+,23+,25+,26+,27-,28-,29+,30+,31-,32+,33-,34+,35-/m0/s1
• InChI key: RIPMDUQTRRLJTE-QHYHXNCWSA-N

Description

General description

Uzarin, also known as Uzarigenin, is a cardenolide glycoside commonly found in plants such as Xysmalobium undulatum, Nerium oleander, Asclepias fruticosa, and Calotropis procera. Existing research suggests that this plant-derived metabolite exerts multiple biological properties, including antidiarrheal, antiviral and anticancer.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

According to the existing research, Uzarin plays potential role as an inhibitor of the SARS-CoV-2 receptor binding domain and SARS-CoV-2 RNA-dependent polymerase, as indicated by molecular docking and dynamics studies.

Features and Benefits

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Other Notes

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Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H300 + H330,H373
• Precautionary Statements: P260 - P264 - P270 - P271 - P304 + P340 + P310 - P314
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - STOT RE 2
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable