description
non-ionic
Quality Level
composition
Sapogenin content, 20-35%
technique(s)
HPLC: suitable
LC/MS: suitable
protein quantification: suitable
sulfated ash
≤10%
Application
Saponins has been used to permeabilize dendritic cells (DCs) for intracellular staining with antibodies.
Biochem/physiol Actions
Saponins are associated with many biological and pharmacological activities. It is known to stimulate immune response in mammals. Saponins possesses antiviral, antifungal, antitumor, anti-inflammatory, hypoglycemic and hypocholesterolemic effects. It is a potent hemolytic, when injected intravaneously. It is also useful as a surfactant to enhance penetration of proteins and other macromolecules through cell membranes. Saponins have also been used as adjuvants for vaccines.
Packaging
10, 25 g in poly bottle
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Mesenchymal stromal/stem cells (MSCs) have been considered an attractive source of cytotherapy due to their promising effects on treating various diseases. Allogeneic MSCs (allo-MSCs) are extensively used in clinical trials due to their convenient preparation and credible performance. Traditionally, allo-MSCs
Advances in saponin-based adjuvants
Sun HX, et al.
Vaccine, 27(12), 1787-1796 (2009)
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