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Key Documents

SAB4501879

Sigma-Aldrich

Anti-MITF antibody produced in rabbit

affinity isolated antibody

Synonym(s):

MITF M1, Microphthalmia-associated transcription factor

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About This Item

MDL number:
MFCD03097016
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 58 kDa

species reactivity

mouse, human

concentration

~1 mg/mL

technique(s)

ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

O75030

UniProt accession no.

O75030

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MITF(4286)

General description

Anti-MITF Antibody detects endogenous levels of total MITF protein.
Anti-MITF Antibody detects endogenous levels of total MITF protein. MITF (microphthalmia-associated transcription factor) is a basic helix-loop-helix, leucine-zipper transcription factor. It is located on human chromosome 3p13.

Immunogen

The antiserum was produced against synthesized peptide derived from human MITF.

Immunogen Range: 151-200

Biochem/physiol Actions

MITF (microphthalmia-associated transcription factor) participates in the growth and differentiation of melanocytes. Mutations in MITF results in waardenburg syndrome type IIa.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The Association of Weight Loss and Cardiometabolic Outcomes in Obese Children: Systematic Review and Meta-regression.
Tamim R, et al.
The Journal of Clinical Endocrinology and Metabolism, 102(3), 758?762-758?762 (2017)
Non?Clear Cell Renal Cell Carcinomas: Biological Insights and Therapeutic Challenges and Opportunities.
Gabriel G M, et al,
Clinical Advances in Hematology & Oncology : H&O, 15(5), 409-418 (2017)
Bcl2 Regulation by the Melanocyte Master Regulator Mitf Modulates Lineage Survival and Melanoma Cell Viability.
Gael G M, et al.
Cell, 109(6), 707-718 (2002)
Zhigang Cai et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 243(10), 1310-1316 (2014-04-23)
Heparan sulfate proteoglycans (HSPG) are important for embryonic development by means of the regulation of gradient formation and signaling of multiple growth factors and morphogens. Previous studies have shown that Bmp/Shh/Fgf signaling are required for the regionalization of the optic

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