PZ0343

PF-06260414

≥98% (HPLC)

• Synonym(s): 6-[(4R)-tetrahydro-4-methyl-1,1-dioxido-2H-1,2,6-thiadiazin-2-yl]-1-isoquinolinecarbonitrile
• Empirical Formula (Hill Notation): C₁₄H₁₄N₄O₂S
• CAS Number: 1612755-71-1
• Molecular Weight: 302.35
• UNSPSC Code: 12352200
• PubChem Substance ID: 329823852

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: light orange to dark orange
• solubility: DMSO: 5 mg/mL, clear (warmed)
• storage temp.: room temp
• SMILES string: C[C@H](CNS1(=O)=O)CN1C2=CC3=CC=NC(C#N)=C3C=C2
• InChI: 1S/C14H14N4O2S/c1-10-8-17-21(19,20)18(9-10)12-2-3-13-11(6-12)4-5-16-14(13)7-15/h2-6,10,17H,8-9H2,1H3/t10-/m1/s1
• InChI key: ZKAVFOXYJCREBQ-SNVBAGLBSA-N

Description

Biochem/physiol Actions

PF-06260414 is a nonsteriodal selective androgen receptor modulator (SARM). PF-06260414 is being investigated as a treatment for muscle weakening such as that associated with muscular dystrophy and the sarcopenia associated with natural aging. PF-06260414 has anabolic activity without unwanted androgenic activity on reproductive organs, liver or kidneys.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable