MAK008
Hydroxyproline Assay Kit
sufficient for 100 colorimetric tests
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usage
sufficient for 100 colorimetric tests
detection method
colorimetric
relevant disease(s)
dermatological diseases
shipped in
wet ice
storage temp.
2-8°C
Related Categories
General description
Hydroxyproline (4-hydroxyproline) is a non-proteinogenic amino acid formed by the post-translational hydroxylation of proline. Hydroxyproline is a major component of collagen, where it serves to stabilize the helical structure. Because hydroxyproline is largely restricted to collagen, the measurement of hydroxylproline levels can be used as an indicator of collagen content. Conditions that increase collagen turnover can elevate serum and urine hydroxyproline levels. Urine and serum hydroxyproline levels can be used as a marker for bone resorption.
Application
Hydroxyproline Assay Kit has been used to determine the concentration of hydroxyproline and collagen.
Suitability
Suitable for hydroxyproline detection in cell and tissue culture supernatants, urine, plasma, serum, and other biological samples.
Principle
In the Hydroxyproline Assay Kit, hydroxyproline concentration is determined by the reaction of oxidized hydroxyproline with 4-(Dimethylamino)benzaldehyde (DMAB), which results in a colorimetric (560 nm) product, proportional to the hydroxyproline present.
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Product No.
Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Flam. Liq. 2 - Met. Corr. 1 - Ox. Liq. 2 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT RE 2 - STOT SE 3
Target Organs
Central nervous system, Thyroid
Supplementary Hazards
Storage Class Code
5.1B - Oxidizing hazardous materials
WGK
WGK 2
Flash Point(F)
64.4 °F
Flash Point(C)
18 °C
Certificates of Analysis (COA)
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