L7920
β-Lactamase Blend
recombinant, expressed in E. coli
Synonym(s):
Carbapenemase, Cephalosprinase
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About This Item
Recommended Products
recombinant
expressed in E. coli
Quality Level
sterility
γ-irradiated
form
lyophilized powder
storage temp.
2-8°C
General description
No detectable growth in tryptone soy broth at 30-35 °C for 14 days
Biochem/physiol Actions
β-Lactamases exhibit high carbapenemase activity. β-lactamases can destroy the β-lactam ring. True carbapenemases has the ability to hydrolyse several β-lactam ring containing carbapenems like meropenem, doripenem, imipenem and ertapenem.
Components
600-1500 IU beta-lactamase I per vial
60-150 IU beta-lactamase II per vial
60-150 IU beta-lactamase II per vial
Unit Definition
One unit will hydrolyze 1.0 μmole substrate per min (βI: benzylpenicillin; βII: cephalosporin C) in phosphate buffer, pH 7.0 at 25°C.
Physical form
Lyophilized powder containing sodium chloride, potassium phosphate, dipotassium phosphate and sorbitol.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Identification and screening of carbapenemase-producing Enterobacteriaceae
Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(5), 432-438 (2012)
ACS applied materials & interfaces, 11(36), 32599-32604 (2019-08-27)
Antimicrobial resistance (AMR) has been identified as a major threat to public health worldwide. To ensure appropriate use of existing antibiotics, rapid and reliable tests of AMR are necessary. One of the most common and clinically important forms of bacterial
Mechanisms and Detection of Antimicrobial Resistance
Principles and Practice of Pediatric Infectious Diseases (Fourth Edition), 1467-1478 (2017)
Antibiotics (Basel, Switzerland), 9(10) (2020-10-03)
The misuse of antibiotics in health care has led to increasing levels of drug resistant infections (DRI's) occurring in the general population. Most technologies developed for the detection of DRI's typically focus on phenotyping or genotyping bacterial resistance rather than
Prevalence of faecal carriage of NDM-1-producing bacteria among patients with diarrhoea in Bangladesh.
Journal of medical microbiology, 63(Pt 4), 620-622 (2014-02-04)
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