Recommended Products
type
for DNA synthesis
Quality Level
product line
Proligo Reagents
concentration
3.9-4.7 g/L iodine (titration)
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Preparation Note
Tetrahyrofurane/Water/Pyridine/Iodine 90.54/9.05/0.41/0.43 (v/v/v/w)
Other Notes
Oxidizer solution, containing tetrahydrofuran (THF), pyridine, iodine and water, is applied to oxidize the chemically unstable trivalent phosphorous triester linkage formed in the coupling reaction to a stable pentavalent phosphate triester. Iodine functions as a mild oxidant and water functions as an oxygen donor.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
Target Organs
Central nervous system, Respiratory system
Supplementary Hazards
Storage Class Code
3 - Flammable liquids
WGK
WGK 1
Flash Point(F)
-2.0 °F - closed cup
Flash Point(C)
-18.9 °C - closed cup
Certificates of Analysis (COA)
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