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GE17-5317-10

Capto™ MMC

Cytiva 17-5317-10, pack of 25 mL

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About This Item

UNSPSC Code:
23151817
NACRES:
NA.56

description

Ion Exchanger Type (value)

packaging

pack of 25 mL

manufacturer/tradename

Cytiva 17-5317-10

matrix

highly cross-linked agarose

avg. part. size

75 μm (d50v)

cleaning in place

2-14

working range

2-12

capacity

>45 mg binding capacity (BSA/ml medium at 30 mS/cm)

suitability

suitable for bioprocess medium

General description

Capto™ MMC is a multimodal cation exchanger with a different selectivity, compared with traditional ion exchangers. It can be used to bind proteins at the conductivity of the feed material and to solve specific purification challenges.
Dynamic binding capacity at 10% breakthrough as measured at a residence time of 2 min, 300 cm/h in a Tricorn 5/100 column with 10-cm bed height in 50 mM Sodium acetate, pH 4.75, 250 mM NaCl.

Application

Capto™ MMC is a multimodal cation exchanger, belonging to the Capto™ family of BioProcess media for fast, efficient and cost-effective Protein purification. Capto™ MMC combines Agarose base matrix developments with innovative ligand chemistry. It is composed of a rigid, high-fLow Agarose matrix and a novel multimodal ligand. The multimodal functionality gives Capto™ MMC a different selectivity, compared with traditional ion exchangers. It can be used to bind Proteins at the conductivity of the feed material and to solve specific purification challenges at both high and Low ionic strengths.

The ligand contains caroxylic group and thus its features partly resemble a weak cation exchanger, but for Capto™ MMC also several other types of interactions are involved, including hydrogen bonding and hydrophobic interactions.

Capto™ MMC is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess media range, Capto™ MMC meets industrial demands with security of supply and comprehensive technical and regulatory support.

Features and Benefits

  • Multimodal cation exchanger with a novel selectivity.
  • High dynamic binding capacity at high conductivity increases productivity
  • High-volume throughput cuts process times
  • Smaller unit operations give cost-effective processing and reduce investments

Storage and Stability

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol)

Analysis Note

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Legal Information

Capto is a trademark of Cytiva

Pictograms

Flame
GHS02

Signal Word

Warning

Hazard Statements

H226

Storage Class Code

3 - Flammable liquids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Capto MMC

Capto MMC is a multimodal cation exchanger with the properties of a weak cation exchanger. In addition to electrostatic interactions, the ligand structure provides for additional interaction modes such as hydrophobic interaction, hydrogen bonding, and thiophilic interaction.

Maintenance of Multimodal Chromatography Media and Storage Conditions

This page describes the maintenance of media and storage conditions for multimodal chromatography using GE Healthcare products.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service