G1013
Gly-Arg 4-methoxy-β-naphthylamide dihydrochloride
dipeptidyl aminopeptidase I substrate
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About This Item
Empirical Formula (Hill Notation):
C19H26N6O3 · 2HCl
CAS Number:
Molecular Weight:
459.37
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
Recommended Products
Quality Level
Assay
≥98% (TLC)
form
powder
solubility
ethanol: 20 mg/mL, clear, colorless to yellow
storage temp.
2-8°C
SMILES string
Cl.COc1cc(NC(=O)C(CCCNC(N)=N)NC(=O)CN)cc2ccccc12
InChI
1S/C19H26N6O3.ClH/c1-28-16-10-13(9-12-5-2-3-6-14(12)16)24-18(27)15(25-17(26)11-20)7-4-8-23-19(21)22;/h2-3,5-6,9-10,15H,4,7-8,11,20H2,1H3,(H,24,27)(H,25,26)(H4,21,22,23);1H
InChI key
ZMJQLLSJSFQLTM-UHFFFAOYSA-N
Application
Gly-Arg 4-methoxy-β-naphthylamide dihydrochloride has been used as a substrate to measure the dipeptidyl peptidase I (DPPI) activity in human leukemia cell line.
Substrates
Substrate for dipeptidyl aminopeptidase I
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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M J McGuire et al.
Archives of biochemistry and biophysics, 295(2), 280-288 (1992-06-01)
The lysosomal hydrolase, dipeptidyl peptidase I (DPPI), was purified from human spleen and its enzymatic activity characterized. The enzyme was purified to apparent homogeneity by a combination of differential pH solubility, heat-treatment, affinity chromatography on concanavalin A-agarose and p-hydroxymercuribenzoate-agarose, and
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