Skip to Content
Merck
All Photos(1)

Key Documents

D9565

Sigma-Aldrich

β-Defensin 1 human

≥98% (HPLC and SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder (from 10 mM acetic acid)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

MDL number:
MFCD01865661
UNSPSC Code:
12352202
NACRES:
NA.32

recombinant

expressed in E. coli

Assay

≥98% (HPLC and SDS-PAGE)

form

lyophilized powder (from 10 mM acetic acid)

mol wt

estimated mol wt 3.9 kDa

UniProt accession no.

P60022

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria
fungi
viruses

Mode of action

cell wall synthesis | interferes

storage temp.

−20°C

Gene Information

human ... DEFB1(1672)

Amino Acid Sequence

Asp-His-Tyr-Asn-Cys-Val-Ser-Ser-Gly-Gly-Gln-Cys-Leu-Tyr-Ser-Ala-Cys-Pro-Ile-Phe-Thr-Lys-Ile-Gln-Gly-Thr-Cys-Tyr-Arg-Gly-Lys-Ala-Lys-Cys-Cys-Lys [Disulfide bridges 5-34, 12-27, and 17-35]

General description

Chemical structure: peptide

Biochem/physiol Actions

A small cationic peptide which demonstrates anti-microbial activity. Originally isolated from human plasma, this substance is constitutively expressed in mucosal membrane epithelium.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Antimicrobial Peptides

With bacterial resistance and emerging infectious diseases becoming potential threats to humans, ribosomally synthesized antimicrobial peptides have become a promising focus area in antibiotic research.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service