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A6512

Sigma-Aldrich

L-Arginine β-naphthylamide hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C16H21N5O · HCl
CAS Number:
18905-73-2
Molecular Weight:
335.83
EC Number:
242-654-1
MDL number:
MFCD00051283
UNSPSC Code:
12352204
PubChem Substance ID:
24891096
NACRES:
NA.83
Pricing and availability is not currently available.

Assay

≥98% (TLC)

Quality Level

200

form

powder

solubility

ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

−20°C

SMILES string

Cl.N[C@@H](CCCNC(N)=N)C(=O)Nc1ccc2ccccc2c1

InChI

1S/C16H21N5O.ClH/c17-14(6-3-9-20-16(18)19)15(22)21-13-8-7-11-4-1-2-5-12(11)10-13;/h1-2,4-5,7-8,10,14H,3,6,9,17H2,(H,21,22)(H4,18,19,20);1H/t14-;/m0./s1

InChI key

WEVOXPYVEJEKIT-UQKRIMTDSA-N

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GGTI 298 trifluoroacetate salt hydrate ≥90% (HPLC), film

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GGTI-2133 ≥98% (HPLC), solid

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GGTI-2133

GGTI-286 dihydrochloride ≥90% (HPLC)

SML1186

GGTI-286 dihydrochloride

FFN511 trifluoroacetate salt hydrate ≥98% (HPLC)

F9932

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form

film, lyophilized

form

solid

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

DMSO: >20 mg/mL

solubility

DMSO: 25 mg/mL, H2O: insoluble

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: ≥20 mg/mL

color

colorless

color

white to beige

color

white to light brown

color

yellow

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H351

Precautionary Statements

P281

Hazard Classifications

Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Lot/Batch Number
    029K1201V
    079K1686V
    079K1686
    029K1201
    017K1027

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    Yu-Chih Wang et al.
    Veterinary microbiology, 142(3-4), 309-312 (2009-11-17)
    Enrofloxacin (ER) resistant Actinobacillus pleuropneumoniae strains emerged in Taiwan in 2002. The mechanism of ER resistance in A. pleuropneumoniae has not yet been reported. A total of 48 A. pleuropneumoniae isolates were obtained from the lungs of pigs with pleuropneumonia
    S Kawata et al.
    Journal of biochemistry, 88(6), 1601-1605 (1980-12-01)
    Porcine liver aminopeptidase B[EC 3.4.11.6] is highly specific for hydrolysis of beta-naphthylamides of basic L-amino acids; the Km values for L-arginine beta-naphthylamide and L-lysine beta-naphthylamide were 0.035 and 0.12 mM, respectively. The enzyme was inhibited by various alpha-amino acids. Among
    H Kuramochi et al.
    The Journal of antibiotics, 40(11), 1605-1611 (1987-11-01)
    The action of ubenimex on aminopeptidase (APase) activity was studied in intact spleen cells and peritoneal macrophages from mice. Ubenimex strongly inhibited hydrolyzing activities against arginine-beta-naphtylamide (Arg-NA), Lys-NA and Pro-NA in both cells. Inhibition of hydrolysis of Leu-NA, Met-NA and
    F Willenbrock et al.
    The Biochemical journal, 227(2), 521-528 (1985-04-15)
    The pH-dependences of kcat, Km and kcat./Km for the hydrolysis at 25 degrees C at I 0.1 of L-arginine 2-naphthylamide catalysed by cathepsin H from bovine spleen were determined in the pH range approx. 4-8. The pH-dependences of these kinetic
    T Matsuzawa
    Endocrinologia japonica, 28(4), 469-475 (1981-08-01)
    The substrate specificity of rat testicular and epididymal peptidase was investigated using chromogenic substrates, D. L-alanine-, L-arginine-, gamma-N-L-glutamine-, L-leucine-, D. L-methionine-, alpha-N-benzoyl-D. L-arginine-, and N-benzoyl-L-leucine-beta-naphthylamide. The histochemical distribution of peptidase activity demonstrated with these substrates was also investigated in the
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