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Key Documents

319236

Sigma-Aldrich

Phenolphthalein solution

0.5 wt. % in ethanol: water (1:1)

Synonym(s):

C20H14O4; Phthalin;3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one

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About This Item

Empirical Formula (Hill Notation):
C20H14O4
CAS Number:
Molecular Weight:
318.32
Beilstein:
284423
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

form

liquid

Quality Level

concentration

0.5 wt. % in ethanol: water (1:1)

color

colorless

visual transition interval

8.0-10, colorless to red

mp

-35 °C

density

0.918 g/mL at 25 °C

λmax

552 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1ccc(cc1)C2(OC(=O)c3ccccc23)c4ccc(O)cc4

InChI

1S/C20H14O4/c21-15-9-5-13(6-10-15)20(14-7-11-16(22)12-8-14)18-4-2-1-3-17(18)19(23)24-20/h1-12,21-22H

InChI key

KJFMBFZCATUALV-UHFFFAOYSA-N

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General description

Phenolphthalein is an acid base indicator. It is a weak acid, which is colorless in acidic solution and turns puce pink in alkaline solution. Phenolphthalein is genotoxic. It might cause oxidative damage and binds to estrogen receptors.
Phenolphthalein solution is a synthetic indicator. It is colorless in acidic and neutral conditions. Phenolphthalein gives pink color when added to a base, therefore it is considered as a base indicator.

Application

Phenolphthalein solution has been used to measure total titratable acids by titration method.

Pictograms

FlameExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

75.2 °F - closed cup

Flash Point(C)

24 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH SVHC Candidate List

CAS No.

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Charu Maini
Headstart Science (CCE), 7 (2017)
Cytokinin Treatment Modifies Litchi Fruit Pericarp Anatomy Leading to Reduced Susceptibility to Post-harvest Pericarp Browning
Fahima A, et al.
Plant Science (2019)
Phenolphthalein laxatives and risk of cancer
Coogan PF, et al.
Journal of the National Cancer Institute, 92(23), 1943-1944 (2000)
Physical Chemistry: Understanding our Chemical World (2008)
Amit Fahima et al.
Plant science : an international journal of experimental plant biology, 283, 41-50 (2019-05-28)
Litchi (Litchi chinensis Sonn.) is a subtropical fruit known for its attractive red pericarp color, semi-translucent white aril and unique flavor and aroma. Rapid post-harvest pericarp browning strictly limits litchi fruit marketing. In the current research, we hypothesized that modification

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