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309052

Sigma-Aldrich

Quinoline Yellow

Mixture of the mono- and disulfonic acids of Quinoline Yellow

Synonym(s):

Acid Yellow 3

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About This Item

CAS Number:
8004-92-0
Colour Index Number:
47005
UNSPSC Code:
12171500
NACRES:
NA.47

Quality Level

200

form

powder

technique(s)

titration: suitable

solubility

H2O: soluble
spirit: soluble (23,413-3)

λmax

412 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

InChI

1S/C18H11NO8S2.2Na/c20-17-11-3-1-2-4-12(11)18(21)15(17)13-6-5-9-7-10(28(22,23)24)8-14(16(9)19-13)29(25,26)27;;/h1-8,15H,(H,22,23,24)(H,25,26,27);;/q;2*+1/p-2

InChI key

FZUOVNMHEAPVBW-UHFFFAOYSA-L

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General description

Quinoline Yellow is a yellow, water-soluble, anionic quinophthalone dye. This synthetic dye is generally used as a food additive. Its applications are also seen in the cosmetic and pharmaceutical industries. It is a chinophthalon derivative applied in the compositions of skin, lips, or body cosmetics.Studies show that Quinoline Yellow is not genotoxic or carcinogenic. It is considered to be safe for human health.

Application

Quinoline Yellow has been used as an absorber for the fabrication of the micro-phantoms.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SHBN7870
SHBM4471
SHBL2226
MKCF6185
MKCB9473

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A Weisz et al.
Journal of chromatography. A, 923(1-2), 87-96 (2001-08-21)
The main components of the color additive D&C Yellow No. 10 (Quinoline Yellow, Color Index No. 47005), 2-(2-quinolinyl)-1H-indene-1,3(2H)-dione-6'-sulfonic acid (6SA) and 2-(2-quinolinyl)-1H-indene-1,3(2H)-dione-8'-sulfonic acid (8SA), were isolated from the dye mixture by pH-zone-refining counter-current chromatography (CCC) in the ion-exchange mode. These
Karen Lau et al.
Toxicological sciences : an official journal of the Society of Toxicology, 90(1), 178-187 (2005-12-15)
Exposure to non-nutritional food additives during the critical development window has been implicated in the induction and severity of behavioral disorders such as attention deficit hyperactivity disorder (ADHD). Although the use of single food additives at their regulated concentrations is
Quinoline Yellow dye-induced fixed food-and-drug eruption.
Camille Leleu et al.
Contact dermatitis, 68(3), 187-188 (2013-02-21)
Methyldopa-induced skin rash.
G Gidseg
Southern medical journal, 79(3), 389-389 (1986-03-01)
Hisao Oka et al.
Journal of chromatography. A, 989(2), 249-255 (2003-03-26)
Quinoline yellow (Color Index No. 47005) consists of multiple components that show a large difference in their partition coefficients (K), ranging from 0.03 to 3.3 in the solvent system tert.-butyl methyl ether (MTBE)-1-butanol-acetonitrile-aqueous 0.1 M trifluoroacetic acid (TFA). Consequently, it
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