ABT1488

Anti-MCAM/CD146 Antibody

• UNSPSC Code: 12352203
• eCl@ss: 32160702

Properties

• antibody form: affinity purified immunoglobulin
• Quality Level: 100
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human, rabbit
• concentration: (Please refer to lot specific datasheet.)
• technique(s): immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• UniProt accession no.: P43121

Description

General description

KLH-conjugated linear peptide corresponding to a sequence from the third C2-type Ig-like domain of human MCAM/CD146.

Specificity

Expected to react with both spliced isoforms of human MCAM/CD146 reported by UniProt (P43121).

Application

Epitope: C2-type Ig-like domain 3.

Quality

Evaluated by Western Blotting in HeLa cell lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected MCAM/CD146 in 10 µg of HeLa cell lysate.

Physical properties

~113 kDa observed. Target band size appears larger than the calculated molecular weights of 70.90 kDa (isoform 1) and 56.89 kDa (isoform 2) due to glycosylation.

Physical form

Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids