07-239
Anti-mGluR7 Antibody
Upstate®, from rabbit
Synonym(s):
Anti-GLUR7, Anti-MGLU7, Anti-MGLUR7, Anti-NEDSHBA, Anti-PPP1R87
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... GRM7(2917)
Specificity
mGluR7
Immunogen
peptide (C-NSPAAKKKYVSYNN) corresponding to amino acids 899-912 of human mGluR7
Application
Detect mGluR7 using this Anti-mGluR7 Antibody validated for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Vesicular Trafficking
Neurodegenerative Diseases
Vesicular Trafficking
Neurodegenerative Diseases
Quality
routinely evaluated by immunoblot on rat brain microsomal preparation
Target description
97kDa
Physical form
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A chromatography
Storage and Stability
2 years at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses.
Paulo S Pinheiro, David Perrais, Francoise Coussen, Jacques Barhanin, Bernhard Bettler et al.
Proceedings of the National Academy of Sciences of the USA null
Nicole M Fisher et al.
JCI insight, 6(4) (2021-01-22)
The metabotropic glutamate receptor 7 (mGlu7) is a G protein-coupled receptor that has been recently linked to neurodevelopmental disorders. This association is supported by the identification of GRM7 variants in patients with autism spectrum disorder, attention deficit hyperactivity disorder, and
Anatomy and function of group III metabotropic glutamate receptors in gastric vagal pathways.
Richard L Young,Nicole J Cooper,L Ashley Blackshaw
Neuropharmacology null
Tevye Jason Stachniak et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 41(39), 8150-8162 (2021-08-13)
Throughout development, neuronal identity is controlled by key transcription factors that determine the unique properties of a cell. During embryogenesis, the transcription factor Prox1 regulates VIP-positive cortical interneuron migration, survival, and connectivity. Here, we explore the role of Prox1 as
James A Daniel et al.
eLife, 6 (2017-06-10)
SUMO1-conjugation of proteins at neuronal synapses is considered to be a major post-translational regulatory process in nerve cell and synapse function, but the published evidence for SUMO1-conjugation at synapses is contradictory. We employed multiple genetic mouse models for stringently controlled
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