870714P

14:0 Coenzyme A

Avanti Polar Lipids 870714P, powder

• Synonym(s): myristoyl Coenzyme A (ammonium salt)
• Empirical Formula (Hill Notation): C₃₅H₇₁N₁₀O₁₇P₃S
• CAS Number: 799812-85-4
• Molecular Weight: 1028.98
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 5 mg (870714P-5mg)
• manufacturer/tradename: Avanti Polar Lipids 870714P
• application(s): lipidomics
• lipid type: coenzymes
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O[C@@](C(NCCC(NCCSC(CCCCCCCCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]
• InChI: 1S/C35H62N7O17P3S.3H3N/c1-4-5-6-7-8-9-10-11-12-13-14-15-26(44)63-19-18-37-25(43)16-17-38-33(47)30(46)35(2,3)21-56-62(53,54)59-61(51,52)55-20-24-29(58-60(48,49)50)28(45)34(57-24)42-23-41-27-31(36)39-22-40-32(27)42;;;/h22-24,28-30,34,45-46H,4-21H2,1-3H3,(H,37,43)(H,38,47)(H,51,52)(H,53,54)(H2,36,39,40)(H2,48,49,50);3*1H3/t24-,28?,29+,30+,34-;;;/m1.../s1
• InChI key: DSAPDQDCGNIALG-YNLIGXKZSA-N

Description

General description

14:0 Coenzyme A, also known as myristoyl coenzyme A, is a coenzyme A derivative of myristic acid. 14:0 Coenzyme A is a long-chain acyl CoA.

Application

14:0 Coenzyme A may be used as a standard in quantitative ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for simultaneous analysis of tissue long-chain acyl-CoA (LCACoA) concentration.

Biochem/physiol Actions

14:0 Coenzyme A is an important lipid metabolite. It acts as a N-myristoyltransferase substrate during myristoylation. Myristoylation is a protein lipid modification involving the addition of myristoyl group to proteins either during translation to modify protein activity or post-translationally in apoptotic cells.

Packaging

5 mL Amber Glass Screw Cap Vial (870714P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids