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858124P

Avanti

18:0 Lyso PG

Avanti Research™ - A Croda Brand

Synonym(s):

1-octadecanoyl-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); PG(18:0/0:0); 110713

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About This Item

Empirical Formula (Hill Notation):
C24H48O9PNa
CAS Number:
326495-23-2
Molecular Weight:
534.60
UNSPSC Code:
51191904
NACRES:
NA.25

description

1-stearoyl-2-hydroxy-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)

Assay

>99% (LPG; may contain up to 10% of the 2-LPG isomer, TLC)

form

powder

packaging

pkg of 1 × 1 g (858124P-1g)
pkg of 1 × 500 mg (858124P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

General description

18:0 Lyso phosphoglycerol is a synthetic lysophosphatidylglycerol. Lysophospholipids are produced in γ-proteobacteria by lipoprotein acyltransferase activity. These lipids are found in minimal amount in normal bacterial membranes.

Biochem/physiol Actions

Lyso phosphoglycerol (Lyso PG) and acyl-CoA acts as a substrate for lysophosphatidylglycerol acyltransferase 1 (LPGAT1) to synthesize phosphoglycerol. Lyso-phospholipids are nonbilayer-forming lipids. Accumulation of lysophospholipids in bacterial membranes disrupt the membrane integrity due to its detergent- like physical property.

Packaging

20 mL Clear Glass Screw Cap Vial (858124P-1g)
20 mL Clear Glass Screw Cap Vial (858124P-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sidra Iqbal et al.
Plant physiology and biochemistry : PPB, 147, 101-112 (2019-12-20)
Plant phospholipase A (PLA) and C (PLC) families are least explored in terms of structure, diversity and their roles in membrane lipid remodeling under stress conditions. In this study, we performed gene family analysis, determined gene expression in different tissues
Substrate selectivity of lysophospholipid transporter LplT involved in membrane phospholipid remodeling in Escherichia coli
Lin Y, et al.
The Journal of Biological Chemistry, 291(5), 2136-2149 (2016)
Dumindika A Siriwardane et al.
International journal of pharmaceutics, 578, 119077-119077 (2020-01-29)
Identification and quantification of excipient related degradation products in the liposomal formulation is important, as they may impact the safety and efficacy of the drug. Phospholipids are one of the major excipients in liposome drugs composing the lipid bilayer, and
Hideo Shindou et al.
The Journal of biological chemistry, 284(1), 1-5 (2008-08-23)
Cell membranes contain several classes of glycerophospholipids, which have numerous structural and functional roles in the cells. Polyunsaturated fatty acids, including arachidonic acid and eicosapentaenoic acid, are located at the sn-2 (but not sn-1)-position of glycerophospholipids in an asymmetrical manner.

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