Skip to Content
Merck
All Photos(2)

Documents

850725C

Avanti

18:1 (Δ9-Cis) PE (DOPE)

Avanti Polar Lipids

Synonym(s):

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; DOPE; PE(18:1(9Z)/18:1(9Z)); 110635

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C41H78NO8P
CAS Number:
4004-05-1
Molecular Weight:
744.03
UNSPSC Code:
51191904
NACRES:
NA.25

description

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, chloroform solution

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850725C-25mg)
pkg of 2 × 20 mL (850725C-1g)
pkg of 2 × 4 mL (850725C-200mg)
pkg of 5 × 4 mL (850725C-500mg)

manufacturer/tradename

Avanti Polar Lipids

concentration

10 mg/mL (850725C-25mg)
25 mg/mL (850725C-1g)
25 mg/mL (850725C-200mg)
25 mg/mL (850725C-500mg)

application(s)

advanced drug delivery

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38,42H2,1-2H3,(H,45,46)/b19-17-,20-18-/t39-/m1/s1

InChI key

MWRBNPKJOOWZPW-NYVOMTAGSA-N

Application

18:1 (Δ9-Cis) PE (DOPE) has been used:
  • as a lipid standard in the optimization of the liquid chromatography–mass spectrometry (LC-MS)
  • to investigate its impact on antiphosphatidylethanolmine (aPE) enzyme-linked immunosorbent assay (ELISA)
  • to measure its monolayer spontaneous curvature C0s

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850725C-1g)
5 mL Clear Glass Sealed Ampule (850725C-200mg)
5 mL Clear Glass Sealed Ampule (850725C-25mg)
5 mL Clear Glass Sealed Ampule (850725C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Differential dependencies on [Ca 2+] and temperature of the monolayer spontaneous curvatures of DOPE, DOPA and cardiolipin: effects of modulating the strength of the inter-headgroup repulsion
Chen YF, et al.
Soft Matter, 11(20), 4041-4053 (2015)
Jamie Burrell et al.
Langmuir : the ACS journal of surfaces and colloids, 33(44), 12804-12813 (2017-10-06)
Oxylipins, or fatty aldehydes, are a class of molecules produced from membrane lipids as a result of oxidative stress or enzyme-mediated peroxidation. Here we report the effects of two biologically important fatty aldehydes, trans,trans-2,4-decanedienal (DD) and cis-11-hexadecenal (HD), on the
Matthias Dittrich et al.
Langmuir : the ACS journal of surfaces and colloids (2018-09-01)
Colloidal nucleic acid carrier systems based on cationic lipids are a promising pharmaceutical tool in the implementation of gene therapeutic strategies. This study demonstrates the complex behavior of DNA at the lipid-solvent interface facilitating structural changes of the lyotropic liquid-crystalline
Tatiana K Rostovtseva et al.
The Journal of biological chemistry, 287(35), 29589-29598 (2012-07-06)
Elucidating molecular mechanisms by which lipids regulate protein function within biological membranes is critical for understanding the many cellular processes. Recently, we have found that dimeric αβ-tubulin, a subunit of microtubules, regulates mitochondrial respiration by blocking the voltage-dependent anion channel
The outcome of ELISA for antiphosphatidylethanolamine antibodies is dependent on the composition of phosphatidylethanolamine
Hou S, et al.
Journal of Immunological Methods, 440, 27-34 (2017)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service