840008P

Lyso PAF (from Heart PC)

Avanti Polar Lipids 840008P, powder

• Synonym(s): 1-alkyl-2-hydroxy-sn-glycero-3-phosphocholine
• CAS Number: 52691-62-0
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 5 mg (840008P-5mg)
• manufacturer/tradename: Avanti Polar Lipids 840008P
• lipid type: phospholipids; phosphoglycerides
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COCCCCCCCCCCCCCCCC
• InChI: 1S/C24H52NO6P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-29-22-24(26)23-31-32(27,28)30-21-19-25(2,3)4/h24,26H,5-23H2,1-4H3/t24-/m1/s1
• InChI key: VLBPIWYTPAXCFJ-XMMPIXPASA-N

Description

General description

Lyso-platelet activating factor (lyso-PAF) is the alkyl homolog of lysophosphatidylcholine.

Application

Lyso PAF (from Heart PC) (1-alkyl-2-hydroxy-sn-glycero-3-phosphocholine) has been used to study its inhibitory actions on alkyl-PAF-induced death in Swiss albino mice. It may be used as an acyl acceptor in the determination of lysophosphatidic acid (LPA) acyltransferase (LPAAT) activity.

Biochem/physiol Actions

Lyso-platelet activating factor (lyso-PAF) can stimulate inflammation in a murine model of pleurisy. It acts as a stable metabolite and a precursor of PAF. The turnover of lyso-PAF to PAF is expected to induce continued inflammation in target organs or tissues.

Packaging

5 mL Clear Glass Sealed Ampule (840008P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable